Otophylloside B 4'''-O-beta-D-oleandropyranoside is a natural C21 steroidal glycoside that exhibits micromolar-level in vitro inhibitory activity against five human tumour cell lines (HL-60, SMMC-7721, A-549, MCF-7, and SW480) with micromolar-level in vitro inhibitory activity, IC₅₀ = 12.2–>40 μM.
Otophylloside B 4'''-O-beta-D-cymaropyranoside is a natural steroidal glycoside that can inhibit the growth of cancer cells such as HepG2, HeLa, and U251 at micromolar concentrations (IC50 = 31.24–38.91 μM), exhibiting cytotoxic and anticancer potential.