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iGluR

Ionotropic glutamate receptors (iGluRs) are ligand-gated ion channels that are activated by the neurotransmitter glutamate.[1] They mediate the majority of excitatory synaptic transmission throughout the central nervous system and are key players in synaptic plasticity, which is important for learning and memory. iGluRs have been divided into four subtypes on the basis of their ligand binding properties (pharmacology) and sequence similarity: AMPA receptors, kainate receptors, NMDA receptors and delta receptors.
Cat. No. Product name CAS No. Purity Chemical Structure
T13480 (S)-(-)-5-Fluorowillardiine 140187-23-1 99.60%
(S)-(-)-5-Fluorowillardiine is a potent and specific agonist of AMPAR.
T0015 Mephenesin 59-47-2 99.63%
Mephenesin is a centrally acting muscle relaxant with a short duration of action.
T2362 QNZ46 1237744-13-6 99.64%
QNZ46 is a NR2C/NR2D-selective NMDA receptor non-competitive antagonist.
T1186 Ifenprodil Tartrate 23210-58-4 99.7%
Ifenprodil is a selective NMDA receptor (glutamate) antagonist.
T2A2497 L-Glutamic acid 56-86-0 99.7%
(S)-Glutamic acid acts as an excitatory transmitter, shows a direct activating effect on the release of DA from dopaminergic terminals.
T0426 Piracetam 7491-74-9 99.72%
Piracetam, a cyclic derivative of the neurotransmitter gamma-aminobutyric acid (GABA), is used in therapy of the extensive cognitive disorders.
T4885 (-)-Aspartic acid 1783-96-6 99.74%
D-Aspartic acid (D-Asp) is an endogenous amino acid existing in invertebrates and vertebrates. It can regulate testosterone synthesis and is an agonist of NMDA r...
T17293 ZL006 1181226-02-7 99.75%
ZL006 is an effective inhibitor of nNOS/PSD-95 interaction. ZL006 also inhibits NMDA receptor-mediated NO synthesis.
T0333 Aniracetam 72432-10-1 99.8%
Aniracetam(Ro 13-5057), a nootropic and neuroprotective drug, selectively modulates the AMPA receptor and nAChR.
T6608 NMDA 6384-92-5 99.81%
N-Methyl-D-aspartic acid is an amino acid that, as the D-isomer, is the defining agonist for the NMDA receptor subtype of glutamate receptors.
T3957 Farampator 211735-76-1 99.83%
Farampator (CX-691;Org24448) is a positive modulator of AMPA receptor.
T6259 Dizocilpine 77086-21-6 99.85%
MK-801 (Dizocilpine) is a potent N-methyl-D-aspartate (NMDA) receptor antagonist with Ki of 30.5 nM.
T27951 LY392098 211311-39-6 99.85%
LY392098 is an allosteric modulator of AMPA receptor with EC50 of 4.4 μM and can be used in studies about mammalian nervous system.
TQ0233 Traxoprodil 134234-12-1 99.86%
Traxoprodil is a selective NMDA antagonist and protects hippocampal neurons (IC50: 10 nM).
T3026 (-)-Huperzine A 102518-79-6 99.87%
Huperzine A, an active Lycopodium alkaloid extracted from the traditional Chinese herb, is a potent, selective and reversible acetylcholinesterase (AChE) inhibit...
T3379 Decanoic Acid 334-48-5 99.87%
Decanoic Acid acts as a non-competitive AMPA receptor antagonist.
T6352 (-)-Dizocilpine maleate 121917-57-5 99.89%
MK-801 is a potent, selective and non-competitive NMDA receptor antagonist with Kd of 37.2 nM in rat brain membranes.
T6504 Flupirtine maleate 75507-68-5 99.9%
Flupirtine maleate, a centrally acting non-opioid analgesia, is the salt form of Flupirtine. It is an NMDA receptor antagonist , and also a specific neuronal pot...
T5385 Radiprodil 496054-87-6 99.9%
Radiprodil (RGH-896) is an orally active and selective NMDA NR2B receptors antagonist. It was a potential treatment of neuropathic pain associated with diabetic ...
T16402 Org-26576 1026791-61-6 99.94%
Org-26576 is a positive allosteric modulator of the AMPA receptor.
(S)-(-)-5-Fluorowillardiine
T13480
(S)-(-)-5-Fluorowillardiine is a potent and specific agonist of AMPAR.
Mephenesin
T0015
Mephenesin is a centrally acting muscle relaxant with a short duration of action.
QNZ46
T2362
QNZ46 is a NR2C/NR2D-selective NMDA receptor non-competitive antagonist.
Ifenprodil Tartrate
T1186
Ifenprodil is a selective NMDA receptor (glutamate) antagonist.
L-Glutamic acid
T2A2497
(S)-Glutamic acid acts as an excitatory transmitter, shows a direct activating effect on the release of DA from dopaminergic terminals.
Piracetam
T0426
Piracetam, a cyclic derivative of the neurotransmitter gamma-aminobutyric acid (GABA), is used in therapy of the extensive cognitive disorders.
(-)-Aspartic acid
T4885
D-Aspartic acid (D-Asp) is an endogenous amino acid existing in invertebrates and vertebrates. It can regulate testosterone synthesis and is an agonist of NMDA r...
ZL006
T17293
ZL006 is an effective inhibitor of nNOS/PSD-95 interaction. ZL006 also inhibits NMDA receptor-mediated NO synthesis.
Aniracetam
T0333
Aniracetam(Ro 13-5057), a nootropic and neuroprotective drug, selectively modulates the AMPA receptor and nAChR.
NMDA
T6608
N-Methyl-D-aspartic acid is an amino acid that, as the D-isomer, is the defining agonist for the NMDA receptor subtype of glutamate receptors.
Farampator
T3957
Farampator (CX-691;Org24448) is a positive modulator of AMPA receptor.
Dizocilpine
T6259
MK-801 (Dizocilpine) is a potent N-methyl-D-aspartate (NMDA) receptor antagonist with Ki of 30.5 nM.
LY392098
T27951
LY392098 is an allosteric modulator of AMPA receptor with EC50 of 4.4 μM and can be used in studies about mammalian nervous system.
Traxoprodil
TQ0233
Traxoprodil is a selective NMDA antagonist and protects hippocampal neurons (IC50: 10 nM).
(-)-Huperzine A
T3026
Huperzine A, an active Lycopodium alkaloid extracted from the traditional Chinese herb, is a potent, selective and reversible acetylcholinesterase (AChE) inhibit...
Decanoic Acid
T3379
Decanoic Acid acts as a non-competitive AMPA receptor antagonist.
(-)-Dizocilpine maleate
T6352
MK-801 is a potent, selective and non-competitive NMDA receptor antagonist with Kd of 37.2 nM in rat brain membranes.
Flupirtine maleate
T6504
Flupirtine maleate, a centrally acting non-opioid analgesia, is the salt form of Flupirtine. It is an NMDA receptor antagonist , and also a specific neuronal pot...
Radiprodil
T5385
Radiprodil (RGH-896) is an orally active and selective NMDA NR2B receptors antagonist. It was a potential treatment of neuropathic pain associated with diabetic ...
Org-26576
T16402
Org-26576 is a positive allosteric modulator of the AMPA receptor.
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