iGluR

Ionotropic glutamate receptors (iGluRs) are ligand-gated ion channels that are activated by the neurotransmitter glutamate.[1] They mediate the majority of excitatory synaptic transmission throughout the central nervous system and are key players in synaptic plasticity, which is important for learning and memory. iGluRs have been divided into four subtypes on the basis of their ligand binding properties (pharmacology) and sequence similarity: AMPA receptors, kainate receptors, NMDA receptors and delta receptors.

Cat. No.	Product name	CAS No.	Purity
T13480	(S)-(-)-5-Fluorowillardiine	140187-23-1	99.60%
T13480	(S)-(-)-5-Fluorowillardiine is a potent and specific agonist of AMPAR.
T0015	Mephenesin	59-47-2	99.63%
T0015	Mephenesin is a centrally acting muscle relaxant with a short duration of action.
T2362	QNZ46	1237744-13-6	99.64%
T2362	QNZ46 is a NR2C/NR2D-selective NMDA receptor non-competitive antagonist.
T1186	Ifenprodil Tartrate	23210-58-4	99.7%
T1186	Ifenprodil is a selective NMDA receptor (glutamate) antagonist.
T2A2497	L-Glutamic acid	56-86-0	99.7%
T2A2497	(S)-Glutamic acid acts as an excitatory transmitter, shows a direct activating effect on the release of DA from dopaminergic terminals.
T0426	Piracetam	7491-74-9	99.72%
T0426	Piracetam, a cyclic derivative of the neurotransmitter gamma-aminobutyric acid (GABA), is used in therapy of the extensive cognitive disorders.
T4885	(-)-Aspartic acid	1783-96-6	99.74%
T4885	D-Aspartic acid (D-Asp) is an endogenous amino acid existing in invertebrates and vertebrates. It can regulate testosterone synthesis and is an agonist of NMDA r...
T17293	ZL006	1181226-02-7	99.75%
T17293	ZL006 is an effective inhibitor of nNOS/PSD-95 interaction. ZL006 also inhibits NMDA receptor-mediated NO synthesis.
T0333	Aniracetam	72432-10-1	99.8%
T0333	Aniracetam(Ro 13-5057), a nootropic and neuroprotective drug, selectively modulates the AMPA receptor and nAChR.
T6608	NMDA	6384-92-5	99.81%
T6608	N-Methyl-D-aspartic acid is an amino acid that, as the D-isomer, is the defining agonist for the NMDA receptor subtype of glutamate receptors.
T3957	Farampator	211735-76-1	99.83%
T3957	Farampator (CX-691;Org24448) is a positive modulator of AMPA receptor.
T6259	Dizocilpine	77086-21-6	99.85%
T6259	MK-801 (Dizocilpine) is a potent N-methyl-D-aspartate (NMDA) receptor antagonist with Ki of 30.5 nM.
T27951	LY392098	211311-39-6	99.85%
T27951	LY392098 is an allosteric modulator of AMPA receptor with EC50 of 4.4 μM and can be used in studies about mammalian nervous system.
TQ0233	Traxoprodil	134234-12-1	99.86%
TQ0233	Traxoprodil is a selective NMDA antagonist and protects hippocampal neurons (IC50: 10 nM).
T3026	(-)-Huperzine A	102518-79-6	99.87%
T3026	Huperzine A, an active Lycopodium alkaloid extracted from the traditional Chinese herb, is a potent, selective and reversible acetylcholinesterase (AChE) inhibit...
T3379	Decanoic Acid	334-48-5	99.87%
T3379	Decanoic Acid acts as a non-competitive AMPA receptor antagonist.
T6352	(-)-Dizocilpine maleate	121917-57-5	99.89%
T6352	MK-801 is a potent, selective and non-competitive NMDA receptor antagonist with Kd of 37.2 nM in rat brain membranes.
T6504	Flupirtine maleate	75507-68-5	99.9%
T6504	Flupirtine maleate, a centrally acting non-opioid analgesia, is the salt form of Flupirtine. It is an NMDA receptor antagonist , and also a specific neuronal pot...
T5385	Radiprodil	496054-87-6	99.9%
T5385	Radiprodil (RGH-896) is an orally active and selective NMDA NR2B receptors antagonist. It was a potential treatment of neuropathic pain associated with diabetic ...
T16402	Org-26576	1026791-61-6	99.94%
T16402	Org-26576 is a positive allosteric modulator of the AMPA receptor.