T13858 |
RA190
|
1617495-03-0
|
98%
|
|
RA190 inhibits proteasome function by covalently binding to cysteine 88 of ubiquitin receptor RPN13.
|
TN1262 |
3-Feruloylquinic acid
|
1899-29-2
|
98%
|
|
3-O-Feruloylquinic acid is a protease inhibitor, it exerts moderate inhibitory effect against AIV (H5N1) in vitro.
|
T7369L |
Gemigliptin Tartrate(911637-19-9 free base)
|
1374639-74-3
|
98%
|
|
Gemigliptin tartrate is a highly selective, reversible and competitive inhibitor of dipeptidyl peptidase-4 (DPP-4). It has an IC50 of 10.3 nM for human recombina...
|
T2493 |
PD 151746
|
179461-52-0
|
98%
|
|
PD151746 is a calpain inhibitor that exhibits a 20-fold selectivity for u-calpain (Ki = 0.26 ± 0.03 μM) over m-calpain (Ki = 5.33 ± 0.77 μM). IC50 value: 0.26 ± ...
|
T2154 |
MG-132
|
133407-82-6
|
98%
|
|
MG-132 is a potent cell-permeable 26S proteasome inhibitor (IC50: 100 nM). It also inhibits calpain (IC50: 1.2 μM).
|
T6583 |
MG-101
|
110044-82-1
|
98%
|
|
MG-101 (ALLN) is a cell-permeable and potent inhibitor of cysteine proteases including calpains and lysosomal cathepsins.
|
T4042 |
Talabostat mesylate
|
150080-09-4
|
98%
|
|
Talabostat mesylate is an orally active, selective inhibitor of dipeptidyl peptidases IV (DPP4, IC50: 0.18 nM), including tumor-associated fibroblast activation ...
|
T14005 |
1G244
|
847928-32-9
|
98%
|
|
1G244 is an inhibitor of DPP8/9 with antiatherosclerotic and antimyeloma properties. 1G244 had the IC50 values of 14 and 53 nM against DPP8 and DPP9, and The Ki ...
|
T10061 |
(1S,2S)-Bortezomib
|
1132709-14-8
|
98%
|
|
(1S,2S)-Bortezomib is an enantiomer of Bortezomib. Bortezomib is a reversible and selective inhibitor of the proteasome with a Ki of 0.6 nM for 20S proteasome.
|
T6432 |
Calpeptin
|
117591-20-5
|
98%
|
|
Calpeptin is a potent, cell-permeable calpain inhibitor.
|
T8397 |
Ixazomib citrate
|
1239908-20-3
|
98%
|
|
Ixazomib citrate is a prodrug of Ixazomib (MMLN-2238). MLN9708 is an orally bioavailable second generation proteasome inhibitor (IC50 of 3.4 nM ) with potential ...
|
T21854 |
Proteasome inhibitor IX
|
856849-35-9
|
98%
|
|
AM 114 is an inhibitor of chymotrypsin-like activity of the 20S proteasome (IC50 ~1 μM). AM 114 shows potent anticancer activity. AM 114 exhibits HCT116 p53+/+ c...
|
T17011 |
TCH-165
|
1446350-60-2
|
98%
|
|
TCH-165 is a small molecule modulator of proteasome assembly, resulting in an increase in 20S levels. The increase in the level of free 20S corresponds to enhanc...
|
T2016 |
MLN9708
|
1201902-80-8
|
98%
|
|
MLN2238 suppresses the chymotrypsin-like proteolytic (β5) site of the 20S proteasome(Ki50=0.93 nM, IC50=3.4 nM/). The biologically active form of MLN9708 is MLN2...
|
T2122 |
Ixazomib
|
1072833-77-2
|
98%
|
|
MLN2238, a second generation, boron-containing peptide proteasome inhibitor (PI), inhibits the chymotrypsin-like proteolytic (β5) site of the 20S proteasome (IC5...
|
T6237 |
Trelagliptin
|
865759-25-7
|
98%
|
|
Trelagliptin is a highly specific and long-acting DPP-4 inhibitor.
|
T12710 |
Retagliptin Phosphate
|
1256756-88-3
|
98%
|
|
Retagliptin Phosphate is pharmaceutical composition of DPP-4 inhibitor, for treating type-2 diabetes.
|
T1502 |
Vildagliptin
|
274901-16-5
|
98%
|
|
Vildagliptin is a cyanopyrrolidine-based, orally bioavailable inhibitor of dipeptidyl peptidase 4 (DPP-4), with hypoglycemic activity. Vildagliptin's cyano moiet...
|
TQ0038 |
Brensocatib
|
1802148-05-5
|
98%
|
|
AZD7986 is a Dipeptidyl peptidase 1 (DPP1) inhibitor (pIC50s: 6.85, 7.7, 7.6, 7.8, and 7.8 in human, rat, mouse, rabbit, and dog, respectively).
|
T9090 |
MUN57694
|
858557-69-4
|
98%
|
|
MUN57694 is an inhibitor of 26S proteasome.
|