T2850 |
Bicuculline
|
485-49-4
|
99.99%
|
|
Bicuculline ((+)-Bicuculline) is a light-sensitive competitive antagonist of GABAA receptors. It was originally identified in 1932 in plant alkaloid extracts and...
|
T1396 |
Bemegride
|
64-65-3
|
99.97%
|
|
Bemegride (3-Ethyl-3-methylglutarimide), a central nervous system stimulant, serves as an antidote for barbiturate poisoning.
|
T8572 |
CL 218872
|
66548-69-4
|
99.97%
|
|
CL 218872 is a benzodiazepine agonist displaying selectivity for α1 subunit-containing GABAA receptors (Ki values are 130, 1820, 1530, > 10000, 490 and > 10000 n...
|
T2339 |
Apalutamide
|
956104-40-8
|
99.97%
|
|
Apalutamide (ARN-509) is a small molecule and androgen receptor (AR) antagonist with potential antineoplastic activity.
|
T0715 |
Chlormezanone
|
80-77-3
|
99.97%
|
|
Chlormezanone (Trancopal) is a non-benzodiazepine that is used in the management of anxiety. It has been suggested for use in the treatment of muscle spasm.
|
T3644 |
U93631
|
152273-12-6
|
99.97%
|
|
GABAA receptor antagonist that binds the picrotoxin site and stabilizes the inactive form of the channel via allosteric interaction. Accelerates the decay of GAB...
|
T22813 |
GS 39783
|
39069-52-8
|
99.94%
|
|
GS 39783 is a positive allosteric modulator (PAM) of GABABR, which reduces the motivational properties of alcohol and the conditioned reinforcement and condition...
|
T2S1464 |
Thiocolchicoside
|
602-41-5
|
99.94%
|
|
Thiocolchicoside (Thiocolchicine 2-glucoside analog) (Muscoril, Myoril, Neoflax) is a muscle relaxant with anti-inflammatory and analgesic effects. It acts as a ...
|
T3173 |
DAA-1106
|
220551-92-8
|
99.94%
|
|
DAA-1106 is a potent and selective ligand for peripheral benzodiazepine receptor (PBR), acting as a potent and selective agonist at the peripheral benzodiazepine...
|
T5375 |
Loreclezole
|
117857-45-1
|
99.94%
|
|
Loreclezole is a selective GABAA receptor modulator and acts as a positive allosteric modulator of β2 or β3-subunit-containing receptors.
|
T8639 |
Phenibut (hydrochloride)
|
3060-41-1
|
99.93%
|
|
Phenibut hydrochloride (3-Amino-4-phenylbutyric acid hydrochloride) is a GABA mimetic that acts as an agonist at GABAB receptors, blocks α2δ subunit-containing v...
|
T13536 |
Afoxolaner
|
1093861-60-9
|
99.93%
|
|
Afoxolaner is an isoxazoline insecticide/acaricide against Ixodes scapularis in dogs. Afoxolaner acts on the insect GABA and glutamate receptors, inhibiting GABA...
|
T0710 |
L-Cycloserine
|
339-72-0
|
99.92%
|
|
L-Cycloserine ((-)-Cycloserine) irreversibly inhibits GABA pyridoxal 5′-phosphate-dependent aminotransferase in E. coli, as well in the brains of various animals...
|
T5330 |
Fluralaner
|
864731-61-3
|
99.90%
|
|
Fluralaner (A1443) is an isoxazoline ectoparasiticide. It potently and selectively inhibits binding of the GABA receptor channel blocker EBOB to housefly head me...
|
T7699 |
AZD7325
|
942437-37-8
|
99.88%
|
|
AZD7325 (AZD-7325) is a GABA-Aα2,3 -selective receptor modulator.
|
T8036 |
6-Methylflavone
|
29976-75-8
|
99.86%
|
|
6-Methylflavone is an activator of α1β2γ2L and α1β2 GABAA receptors.
|
T1065 |
Baclofen
|
1134-47-0
|
99.85%
|
|
Baclofen (Lioresal) is a synthetic chlorophenyl-butanoic acid derivative used to treat spasms due to spinal cord damage and multiple sclerosis, muscle-relaxing B...
|
T8630 |
Baclofen hydrochloride
|
28311-31-1
|
99.83%
|
|
Baclofen hydrochloride (4-amino-3-(4-chlorophenyl)butanoic acid hydron chloride) is a GAMMA-AMINOBUTYRIC ACID derivative that is a specific GABA-B RECEPTORS agon...
|
T11349 |
GABAA receptor agent 1
|
1571-87-5
|
99.83%
|
|
GABAA receptor agent 1 has strong anticonvulsant activity and is a high affinity ligand of GABAA receptor.
|
T9424 |
Temgicoluril
|
10095-06-4
|
99.83%
|
|
Temgicoluril (mebikar) acts on GABA Receptor.
|