GABA Receptor

The GABA receptors are a class of receptors that respond to the neurotransmitter gamma-aminobutyric acid (GABA), the chief inhibitory compound in the mature vertebrate central nervous system. There are two classes of GABA receptors: GABAA and GABAB. GABAA receptors are ligand-gated ion channels (also known as ionotropic receptors); whereas GABAB receptors are G protein-coupled receptors, also called metabotropic receptors.

Cat. No.	Product name	CAS No.	Purity
TN4298	Isohyenanchin	19417-00-6	98%
TN4298	Isohyenanchin is the potent antagonist of RDLac homo-oligomers, it is also a weak antagonist of ionotropic GABA receptors.
T12044	(-)-Bicuculline methochloride	53552-05-9	98%
T12044	(-)-Bicuculline methochloride is a potent antagonist of GABAA receptor.
T3927	Phellopterin	2543-94-4	98%
T3927	Phellopterin is a partial agonist of the central benzodiazepine receptors in vitro. Phellopterin shows a cytotoxic effect on RAW264.7 cell at the concentration f...
T2850	Bicuculline	485-49-4	98%
T2850	Bicuculline is a light-sensitive competitive antagonist of GABAA receptors. It was originally identified in 1932 in plant alkaloid extracts and has been isolated...
T1396	Bemegride	64-65-3	98%
T1396	Bemegride is a central nervous system stimulant and antidote for barbiturate poisoning.
T8572	CL 218872	66548-69-4	98%
T8572	CL 218872 is a benzodiazepine agonist displaying selectivity for α1 subunit-containing GABAA receptors (Ki values are 130, 1820, 1530, > 10000, 490 and > 10000 n...
T2S1464	Thiocolchicoside	602-41-5	98%
T2S1464	Thiocolchicoside (Muscoril, Myoril, Neoflax) is a muscle relaxant with anti-inflammatory and analgesic effects. It acts as a competitive GABAA receptor antagonis...
T5375	Loreclezole	117857-45-1	98%
T5375	Loreclezole is a selective GABAA receptor modulator and acts as a positive allosteric modulator of β2 or β3-subunit-containing receptors.
T8639	Phenibut (hydrochloride)	3060-41-1	98%
T8639	Phenibut (hydrochloride) is a GABA mimetic that acts as an agonist at GABAB receptors, blocks α2δ subunit-containing voltage-gated calcium channels, stimulates d...
T13536	Afoxolaner	1093861-60-9	98%
T13536	Afoxolaner is an isoxazoline insecticide/acaricide against Ixodes scapularis in dogs. Afoxolaner acts on the insect GABA and glutamate receptors, inhibiting GABA...
T7699	AZD7325	942437-37-8	98%
T7699	AZD-7325 is a GABA-Aα2,3 -selective receptor modulator.
T4590	(+)-Kavain	500-64-1	98%
T4590	Kawain is one of the six major kavalactones found in the Piper methysticum (kava) plant; reversible inhibitor of MAO-B.
T8036	6-Methylflavone	29976-75-8	98%
T8036	6-Methylflavone is an activator of α1β2γ2L and α1β2 GABAA receptors.
T1065	Baclofen	1134-47-0	98%
T1065	Baclofen is a synthetic chlorophenyl-butanoic acid derivative used to treat spasms due to spinal cord damage and multiple sclerosis, muscle-relaxing Baclofen act...
T8630	Baclofen hydrochloride	28311-31-1	98%
T8630	Baclofen hydrochloride is a GAMMA-AMINOBUTYRIC ACID derivative that is a specific GABA-B RECEPTORS agonist. It is used in the treatment of MUSCLE SPASTICITY, esp...
T11349	GABAA receptor agent 1	1571-87-5	98%
T11349	GABAA receptor agent 1 has strong anticonvulsant activity and is a high affinity ligand of GABAA receptor.
T11307	Fluxametamide	928783-29-3	98%
T11307	Fluxametamide is a novel isoxazoline insecticide that acts via distinctive antagonism of insect ligand-gated chloride channels, acts as an antagonist of GABA- an...
T0349	Riluzole	1744-22-5	98%
T0349	Riluzole is a glutamate antagonist (RECEPTORS, GLUTAMATE) used as an anticonvulsant (ANTICONVULSANTS) and to prolong the survival of patients with AMYOTROPHIC LA...
T4728	4-Acetamidobutanoic acid	3025-96-5	98%
T4728	4-Acetamidobutanoic acid can be found in blood, feces, and urine, as well as in human prostate tissue. 4-Acetamidobutanoic acid exists in all eukaryotes, ranging...
T2940	6-Hydroxyflavone	6665-83-4	98%
T2940	6-Hydroxyflavone is a noncompetitive inhibitors of cytochrome P450 2C9. It is a flavone, a type of chemical compound. It is reported in leaves of Barleria prioni...