Home Tools
Log in
Cart

GABA Receptor

The GABA receptors are a class of receptors that respond to the neurotransmitter gamma-aminobutyric acid (GABA), the chief inhibitory compound in the mature vertebrate central nervous system. There are two classes of GABA receptors: GABAA and GABAB. GABAA receptors are ligand-gated ion channels (also known as ionotropic receptors); whereas GABAB receptors are G protein-coupled receptors, also called metabotropic receptors.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T2850 Bicuculline 485-49-4 99.99%
Bicuculline
Bicuculline ((+)-Bicuculline) is a light-sensitive competitive antagonist of GABAA receptors. It was originally identified in 1932 in plant alkaloid extracts and...
T1396 Bemegride 64-65-3 99.97%
Bemegride
Bemegride (3-Ethyl-3-methylglutarimide), a central nervous system stimulant, serves as an antidote for barbiturate poisoning.
T8572 CL 218872 66548-69-4 99.97%
CL 218872
CL 218872 is a benzodiazepine agonist displaying selectivity for α1 subunit-containing GABAA receptors (Ki values are 130, 1820, 1530, > 10000, 490 and > 10000 n...
T2339 Apalutamide 956104-40-8 99.97%
Apalutamide
Apalutamide (ARN-509) is a small molecule and androgen receptor (AR) antagonist with potential antineoplastic activity.
T0715 Chlormezanone 80-77-3 99.97%
Chlormezanone
Chlormezanone (Trancopal) is a non-benzodiazepine that is used in the management of anxiety. It has been suggested for use in the treatment of muscle spasm.
T3644 U93631 152273-12-6 99.97%
U93631
GABAA receptor antagonist that binds the picrotoxin site and stabilizes the inactive form of the channel via allosteric interaction. Accelerates the decay of GAB...
T22813 GS 39783 39069-52-8 99.94%
GS 39783
GS 39783 is a positive allosteric modulator (PAM) of GABABR, which reduces the motivational properties of alcohol and the conditioned reinforcement and condition...
T2S1464 Thiocolchicoside 602-41-5 99.94%
Thiocolchicoside
Thiocolchicoside (Thiocolchicine 2-glucoside analog) (Muscoril, Myoril, Neoflax) is a muscle relaxant with anti-inflammatory and analgesic effects. It acts as a ...
T3173 DAA-1106 220551-92-8 99.94%
DAA-1106
DAA-1106 is a potent and selective ligand for peripheral benzodiazepine receptor (PBR), acting as a potent and selective agonist at the peripheral benzodiazepine...
T5375 Loreclezole 117857-45-1 99.94%
Loreclezole
Loreclezole is a selective GABAA receptor modulator and acts as a positive allosteric modulator of β2 or β3-subunit-containing receptors.
T8639 Phenibut (hydrochloride) 3060-41-1 99.93%
Phenibut (hydrochloride)
Phenibut hydrochloride (3-Amino-4-phenylbutyric acid hydrochloride) is a GABA mimetic that acts as an agonist at GABAB receptors, blocks α2δ subunit-containing v...
T13536 Afoxolaner 1093861-60-9 99.93%
Afoxolaner
Afoxolaner is an isoxazoline insecticide/acaricide against Ixodes scapularis in dogs. Afoxolaner acts on the insect GABA and glutamate receptors, inhibiting GABA...
T0710 L-Cycloserine 339-72-0 99.92%
L-Cycloserine
L-Cycloserine ((-)-Cycloserine) irreversibly inhibits GABA pyridoxal 5′-phosphate-dependent aminotransferase in E. coli, as well in the brains of various animals...
T5330 Fluralaner 864731-61-3 99.90%
Fluralaner
Fluralaner (A1443) is an isoxazoline ectoparasiticide. It potently and selectively inhibits binding of the GABA receptor channel blocker EBOB to housefly head me...
T7699 AZD7325 942437-37-8 99.88%
AZD7325
AZD7325 (AZD-7325) is a GABA-Aα2,3 -selective receptor modulator.
T8036 6-Methylflavone 29976-75-8 99.86%
6-Methylflavone
6-Methylflavone is an activator of α1β2γ2L and α1β2 GABAA receptors.
T1065 Baclofen 1134-47-0 99.85%
Baclofen
Baclofen (Lioresal) is a synthetic chlorophenyl-butanoic acid derivative used to treat spasms due to spinal cord damage and multiple sclerosis, muscle-relaxing B...
T8630 Baclofen hydrochloride 28311-31-1 99.83%
Baclofen hydrochloride
Baclofen hydrochloride (4-amino-3-(4-chlorophenyl)butanoic acid hydron chloride) is a GAMMA-AMINOBUTYRIC ACID derivative that is a specific GABA-B RECEPTORS agon...
T11349 GABAA receptor agent 1 1571-87-5 99.83%
GABAA receptor agent 1
GABAA receptor agent 1 has strong anticonvulsant activity and is a high affinity ligand of GABAA receptor.
T9424 Temgicoluril 10095-06-4 99.83%
Temgicoluril
Temgicoluril (mebikar) acts on GABA Receptor.
Bicuculline
T2850
Bicuculline ((+)-Bicuculline) is a light-sensitive competitive antagonist of GABAA receptors. It was originally identified in 1932 in plant alkaloid extracts and...
Bemegride
T1396
Bemegride (3-Ethyl-3-methylglutarimide), a central nervous system stimulant, serves as an antidote for barbiturate poisoning.
CL 218872
T8572
CL 218872 is a benzodiazepine agonist displaying selectivity for α1 subunit-containing GABAA receptors (Ki values are 130, 1820, 1530, > 10000, 490 and > 10000 n...
Apalutamide
T2339
Apalutamide (ARN-509) is a small molecule and androgen receptor (AR) antagonist with potential antineoplastic activity.
Chlormezanone
T0715
Chlormezanone (Trancopal) is a non-benzodiazepine that is used in the management of anxiety. It has been suggested for use in the treatment of muscle spasm.
U93631
T3644
GABAA receptor antagonist that binds the picrotoxin site and stabilizes the inactive form of the channel via allosteric interaction. Accelerates the decay of GAB...
GS 39783
T22813
GS 39783 is a positive allosteric modulator (PAM) of GABABR, which reduces the motivational properties of alcohol and the conditioned reinforcement and condition...
Thiocolchicoside
T2S1464
Thiocolchicoside (Thiocolchicine 2-glucoside analog) (Muscoril, Myoril, Neoflax) is a muscle relaxant with anti-inflammatory and analgesic effects. It acts as a ...
DAA-1106
T3173
DAA-1106 is a potent and selective ligand for peripheral benzodiazepine receptor (PBR), acting as a potent and selective agonist at the peripheral benzodiazepine...
Loreclezole
T5375
Loreclezole is a selective GABAA receptor modulator and acts as a positive allosteric modulator of β2 or β3-subunit-containing receptors.
Phenibut (hydrochloride)
T8639
Phenibut hydrochloride (3-Amino-4-phenylbutyric acid hydrochloride) is a GABA mimetic that acts as an agonist at GABAB receptors, blocks α2δ subunit-containing v...
Afoxolaner
T13536
Afoxolaner is an isoxazoline insecticide/acaricide against Ixodes scapularis in dogs. Afoxolaner acts on the insect GABA and glutamate receptors, inhibiting GABA...
L-Cycloserine
T0710
L-Cycloserine ((-)-Cycloserine) irreversibly inhibits GABA pyridoxal 5′-phosphate-dependent aminotransferase in E. coli, as well in the brains of various animals...
Fluralaner
T5330
Fluralaner (A1443) is an isoxazoline ectoparasiticide. It potently and selectively inhibits binding of the GABA receptor channel blocker EBOB to housefly head me...
AZD7325
T7699
AZD7325 (AZD-7325) is a GABA-Aα2,3 -selective receptor modulator.
6-Methylflavone
T8036
6-Methylflavone is an activator of α1β2γ2L and α1β2 GABAA receptors.
Baclofen
T1065
Baclofen (Lioresal) is a synthetic chlorophenyl-butanoic acid derivative used to treat spasms due to spinal cord damage and multiple sclerosis, muscle-relaxing B...
Baclofen hydrochloride
T8630
Baclofen hydrochloride (4-amino-3-(4-chlorophenyl)butanoic acid hydron chloride) is a GAMMA-AMINOBUTYRIC ACID derivative that is a specific GABA-B RECEPTORS agon...
GABAA receptor agent 1
T11349
GABAA receptor agent 1 has strong anticonvulsant activity and is a high affinity ligand of GABAA receptor.
Temgicoluril
T9424
Temgicoluril (mebikar) acts on GABA Receptor.
1 2 3 4 5 6 7 8 9 10
TargetMol