AChE

Acetylcholinesterase, also known as AChE, AChase or acetylhydrolase, is the primary cholinesterase in the body. It is an enzyme that catalyzes the breakdown of acetylcholine and some other choline esters that function as neurotransmitters. AChE is found at mainly neuromuscular junctions and in chemical synapses of the cholinergic type, where its activity serves to terminate synaptic transmission. It belongs to the carboxylesterase family of enzymes. It is the primary target of inhibition by organophosphorus compounds such as nerve agents and pesticides.

Cat. No.	Product name	CAS No.	Purity
T3026	(-)-Huperzine A	102518-79-6	99.87%
T3026	(-)-Huperzine A (HupA) , an active Lycopodium alkaloid extracted from the traditional Chinese herb, is a potent, selective and reversible acetylcholinesterase (A...
T1575	Nizatidine	76963-41-2	99.87%
T1575	Nizatidine (Acinon) is a competitive and reversible histamine H2-receptor antagonist with antacid activity.
T4S1725	Galanthamine	357-70-0	99.87%
T4S1725	Galanthamine (Galantamine) is an acetylcholinesterase (AChE)inhibitor(IC50 : 500 nM), can reduce brain damage induced by hypoxia-ischemia.
T77560	Histone acetyltransferase p300 Inhibitor 4c	2103-99-3	99.86%
T77560	Histone acetyltransferase p300 Inhibitor 4c is a 2-aminothiazole derivative. Histone acetyltransferase p300 Inhibitor 4c inhibited hCA I, hCA II, AChE and BChE w...
T5S2360	Corydaline	518-69-4	99.86%
T5S2360	1. Corydaline (Corydalin), an isoquinoline alkaloid, is one of the major active constituents in a new prokinetic botanical agent. 2. Corydaline promotes gastric ...
T2S1200	Sinapine	18696-26-9	99.85%
T2S1200	1. Sinapine, an alkaloid from seeds of the cruciferous species, can be used as an effective natural compound for chemo-resistance. 2. Sinapine has antioxidant an...
T0229	Rivastigmine	123441-03-2	99.85%
T0229	Rivastigmine (Exelon) is a Cholinesterase Inhibitor, used for therapy of Alzheimer disease.
T35033	Vamicamide	132373-81-0	99.81%
T35033	Vamicamide (FK 176) is a novel anticholinergic compound. Vamicamide increases spontaneous locomotor activity in mice at 32 mg/kg (p.o.) or higher and inhibits ca...
T7041	Donepezil	120014-06-4	99.8%
T7041	Donepezil (Aricept) is a piperidine-based, potent, specific, and reversible inhibitor of acetylcholinesterase (AChE). It can be used for the treatment of mild to...
TN1786	Isomerazin	1088-17-1	99.8%
TN1786	Isomerazin (Isomeranzin) has anti-inflammatory activity, it suppresses inflammation by inhibiting M1 macrophage polarization through the p65, NF-κB and ERK pathw...
T4912	Jatrorrhizine chloride	6681-15-8	99.79%
T4912	Jatrorrhizine chloride (Neprotine chloride) is a potent and orally active uptake-2 transporter inhibitor. It exhibits a critical neuroprotective role in H2O2-ind...
T0818	Decamethonium bromide	541-22-0	99.79%
T0818	Decamethonium bromide (Syncurine) is a neuromuscular blocker and nicotinic AChR partial agonist.
T35033L	(S)-Vamicamide	151851-72-8	99.76%
T35033L	(S)-Vamicamide is a novel anticholinergic compound.Vamicamide increases spontaneous locomotor activity in mice at 32 mg/kg or higher (p.o.) and inhibits tonic co...
T2S0491	Isoeugenol acetate	93-29-8	99.76%
T2S0491	1. Isoeugenol acetate (Acetylisoeugenol) shows good antifungal activities against R. solani and F. oxysporum. 2. Isoeugenol acetate is a mild sensitizer in vivo....
T1552	Itopride hydrochloride	122892-31-3	99.76%
T1552	Itopride hydrochloride (Ganaton) is an AChE and D2DR inhibitor.
T61969	AChE/BChE-IN-10		99.75%
T61969	AChE/BChE-IN-10 is a potent dual inhibitor of AChE and BChE with IC50 values of 0.176, and 0.47 μM, respectively. AChE/BChE-IN-10 exhibits good blood brain barri...
T2979	DL-Menthol	89-78-1	99.74%
T2979	DL-Menthol ((±)-Menthol) is a racemic mixture of the monoterpene alcohols (–)-menthol and (+)-menthod, which have been found in Cannabis. (–)-Menthol is more com...
TN1527	(-)-Corynoxidine	57906-85-1	99.73%
TN1527	(-)-Corynoxidine is an AChE inhibitor derived from tubers of Stephania succifera. Corynoxidine exhibits antibacterial activities against Staphylococcus aureus an...
T60891	AChE/BChE/MAO-B-IN-1	2416910-82-0	99.69%
T60891	AChE/BChE/MAO-B-IN-1 is a reversible, non-time-dependent inhibitor of AChE, BChE and MAO-B that crosses the blood-brain barrier and exhibits inhibitory effects o...
T2571	Benactyzine hydrochloride	57-37-4	99.68%
T2571	Benactyzine hydrochloride (Neuroleptone) is a centrally acting muscarinic antagonist. Benactyzine has been used in the treatment of depression and is used in res...