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AChE

Acetylcholinesterase, also known as AChE, AChase or acetylhydrolase, is the primary cholinesterase in the body. It is an enzyme that catalyzes the breakdown of acetylcholine and some other choline esters that function as neurotransmitters. AChE is found at mainly neuromuscular junctions and in chemical synapses of the cholinergic type, where its activity serves to terminate synaptic transmission. It belongs to the carboxylesterase family of enzymes. It is the primary target of inhibition by organophosphorus compounds such as nerve agents and pesticides.
Cat. No. Product name CAS No. Purity Chemical Structure
T7213 Demecarium bromide 56-94-0 98%
Demecarium bromide is a potent cholinesterase inhibitor,and is treatment glaucoma agent.
T7114 GALANTHAMINONE 510-77-0 98%
Galanthaminone is a cholinesterase (AChE) inhibitor, is used for the treatment of mild to moderate Alzheimer's disease and various other memory impairments.
T5721 Dehydroevodiamine hydrochloride 111664-82-5 98%
Dehydroevodiamine (DHE), a natural compound isolated from Evodia rutaecarpa, can inhibit AChE. It has hypotensive and neuroprotective effects and modulates nitri...
T7640 Aldicarb sulfone 1646-88-4 98%
Aldicarb sulfone is a cholinesterase inhibitor .
T21825 TAE-1 1414469-59-2 98%
TAE-1 is an inhibitor of amyloid-β fibril formation and aggregation. It inhibits cholinesterases AChE and BuChE with IC50 of 0.3 μM and 3.9 μM, respectively.
T2S1720 Huperzine B 103548-82-9 98%
1. Huperzine-B is a efficient inhibitor of human brain AChE. 2. Huperzine-B can enhance ognitive and protect neuro, may be potentially new drug candidates for Al...
T2S1200 Sinapine 18696-26-9 98%
1. Sinapine, an alkaloid from seeds of the cruciferous species, can be used as an effective natural compound for chemo-resistance. 2. Sinapine has antioxidant an...
T0780 Pyridostigmine bromide 101-26-8 98%
Pyridostigmine bromide is a cholinesterase inhibitor with a slightly longer duration of action than NEOSTIGMINE. It is used in the treatment of myasthenia gravis...
TN1899 Lycoramine 21133-52-8 98%
Lycoramine is a natural product isolated from Lycoris radiate. Lycoramine is a potent acetylcholinesterase (AChE) inhibitor
T2845 Imperatorin 482-44-0 98%
Imperatorin is a modulator of p38, ERK pathway. Imperatorin increases BMP-2 expression (mRNA) and increases bone density/volume and mineralization in vivo.
T1635 Fenchlorphos 299-84-3 98%
Fenchlorphos is a cholinesterase inhibitor, used as an insecticide.
T13469 (±)-Huperzine A 120786-18-7 98%
(±)-Huperzine A is an active Lycopodium alkaloid extracted from traditional Chinese herbs. (±)-Huperzine A is a selective and reversible inhibitor of AChE and ca...
T5S1025 Picfeltarraenin IA 97230-47-2 98%
1. Picfeltarraenin IA, IB, IV, X, XI are stronger AChE inhibitions than the known AChE inhibitor Tacrine.
T23131 PE 154 1192750-33-6 98%
PE 154 is a potent fluorescent inhibitor of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) with IC50s of 280 pM and 16 nM respectively. PE 154 is c...
T9862 Pseudocoptisine chloride 30044-78-1 98%
Pseudocoptisine chloride is isolated from Corydalis Tuber with anti-inflammatory and anti-amnestic properties. Pseudocoptisine chloride inhibits acetylcholineste...
T6S2356 Corynoline 18797-79-0 98%
1. Corynoline is an acetylcholinesterase inhibitor.
TN2443 Chikusetsusaponin Ib 59252-87-8 98%
Chikusetsusaponin Ib is an inhibitor of AChE and can be used in studies about anti-Alzheimer's diseases.
T22329 Ethyl (triphenylphosphoranylidene) acetate 1099-45-2 98%
Ethyl (triphenylphosphoranylidene) acetate may act as an cholinesterase inhibitor that inhibits AChE and BChE.
T3S1612 Kuwanon G 75629-19-5 98%
1. Kuwanon G as dual inhibitors of PTP1B and α-glucosidase enzymes, as well as insulin sensitizers, it may potentially be utilized as an effective treatment for ...
T5S2254 Swertianolin 23445-00-3 98%
1. Swertianolin, mangiferin, rhodenthoside A-C, isoorientin, isovitexin, and amarogentin would serve as potential chemotaxonomic markers to differentiate Gentian...
Demecarium bromide
T7213
Demecarium bromide is a potent cholinesterase inhibitor,and is treatment glaucoma agent.
GALANTHAMINONE
T7114
Galanthaminone is a cholinesterase (AChE) inhibitor, is used for the treatment of mild to moderate Alzheimer's disease and various other memory impairments.
Dehydroevodiamine hydrochloride
T5721
Dehydroevodiamine (DHE), a natural compound isolated from Evodia rutaecarpa, can inhibit AChE. It has hypotensive and neuroprotective effects and modulates nitri...
Aldicarb sulfone
T7640
Aldicarb sulfone is a cholinesterase inhibitor .
TAE-1
T21825
TAE-1 is an inhibitor of amyloid-β fibril formation and aggregation. It inhibits cholinesterases AChE and BuChE with IC50 of 0.3 μM and 3.9 μM, respectively.
Huperzine B
T2S1720
1. Huperzine-B is a efficient inhibitor of human brain AChE. 2. Huperzine-B can enhance ognitive and protect neuro, may be potentially new drug candidates for Al...
Sinapine
T2S1200
1. Sinapine, an alkaloid from seeds of the cruciferous species, can be used as an effective natural compound for chemo-resistance. 2. Sinapine has antioxidant an...
Pyridostigmine bromide
T0780
Pyridostigmine bromide is a cholinesterase inhibitor with a slightly longer duration of action than NEOSTIGMINE. It is used in the treatment of myasthenia gravis...
Lycoramine
TN1899
Lycoramine is a natural product isolated from Lycoris radiate. Lycoramine is a potent acetylcholinesterase (AChE) inhibitor
Imperatorin
T2845
Imperatorin is a modulator of p38, ERK pathway. Imperatorin increases BMP-2 expression (mRNA) and increases bone density/volume and mineralization in vivo.
Fenchlorphos
T1635
Fenchlorphos is a cholinesterase inhibitor, used as an insecticide.
(±)-Huperzine A
T13469
(±)-Huperzine A is an active Lycopodium alkaloid extracted from traditional Chinese herbs. (±)-Huperzine A is a selective and reversible inhibitor of AChE and ca...
Picfeltarraenin IA
T5S1025
1. Picfeltarraenin IA, IB, IV, X, XI are stronger AChE inhibitions than the known AChE inhibitor Tacrine.
PE 154
T23131
PE 154 is a potent fluorescent inhibitor of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) with IC50s of 280 pM and 16 nM respectively. PE 154 is c...
Pseudocoptisine chloride
T9862
Pseudocoptisine chloride is isolated from Corydalis Tuber with anti-inflammatory and anti-amnestic properties. Pseudocoptisine chloride inhibits acetylcholineste...
Corynoline
T6S2356
1. Corynoline is an acetylcholinesterase inhibitor.
Chikusetsusaponin Ib
TN2443
Chikusetsusaponin Ib is an inhibitor of AChE and can be used in studies about anti-Alzheimer's diseases.
Ethyl (triphenylphosphoranylidene) acetate
T22329
Ethyl (triphenylphosphoranylidene) acetate may act as an cholinesterase inhibitor that inhibits AChE and BChE.
kuwanon G
T3S1612
1. Kuwanon G as dual inhibitors of PTP1B and α-glucosidase enzymes, as well as insulin sensitizers, it may potentially be utilized as an effective treatment for ...
Swertianolin
T5S2254
1. Swertianolin, mangiferin, rhodenthoside A-C, isoorientin, isovitexin, and amarogentin would serve as potential chemotaxonomic markers to differentiate Gentian...
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