withanolide a

Withanolide A extends the lifespan in human EGFR-driven cancerous Caenorhabditis elegans.

27-O-(tert-Butyldimethylsilyl)withaferin A (compound 9a), a natural withanolide known for inducing apoptosis, exhibits antiproliferative effects on HeLa, A-549, and MCF-7 human cancer cell lines, as well as on normal Vero cells [1].

Withasomniferolide B, a withanolide, can be obtained through isolation from a methanol extract of Withania somnifera roots, which acts as a positive activator of the GABA(A) receptor [1].

Withasomniferolide A, a withanolide extracted from the roots of Withania somnifera, has been identified as a positive activator of the GABAA receptor, isolated using a methanol extract [1].

Withaphysalin R (compound 5), a withanolide derived from the Solanaceae family, possesses an ergosterol-based steroid ester structure. This compound exhibits notable activities such as cytotoxic, immunosuppressive, antitumor, anti-inflammatory, anticonvulsive, and antioxidant effects [1].

Physagulide J, a withanolide compound extracted from Physalis angulata L., exhibits anti-inflammatory and anti-tumor properties [1].

4,27-Dimethyl withaferin A, a synthetic analog of withanolide natural products, exhibits potential in the study of neurodegenerative diseases[1].

Withanolide, specifically (22R)-27-Hydroxy-1-oxowitha-2,5,24-trienolide, is a natural product that can be isolated from the aerial parts of the halophyte Datura stramonium [1].

Dihydrowithaferin A is a withanolide isolated from Withania somnifera with activity against acetylcholinesterase (AChE). Dihydrowithaferin A in the diet may prevent or decrease the growth of tumors.

Withanolide B is a natural product

2,3-Dihydro-3-methoxywithaferin A is a natural withanolide that exhibits cytotoxicity to human cancer cells and serves as a potential anticancer compound. Additionally, it protects normal cells against stress.

Withanolide C is a natural product from Physali alkekengi.

Withanolide S is a natural product for research related to life sciences. The catalog number is TN5258 and the CAS number is 63139-16-2.