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vx445

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  • Inhibitors & Agonists
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    TargetMol | Inhibitors_Agonists
Elexacaftor
VX-445
T149352216712-66-0
Elexacaftor (VX-445) is a cystic fibrosis transmembrane conductance regulator (CFTR) corrector. It promotes the processing and trafficking of CFTR, increases the amount of CFTR on the cell surface, and improves the processing and trafficking of Phe508del CFTR protein.
  • $89
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TargetMol | Inhibitor Hot
(R)-Elexacaftor
2-O-Glucosyloxy-4-methoxycinnamic acid
T782402229860-99-3
(R)-Elexacaftor (compound 37) is the enantiomer of Elexacaftor (compound 1). (R)-Elexacaftor is a CFTR modulator with an EC50 of 0.29 μM for CFTR dF508.
  • $98
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