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  • Ligand for E3 Ligase
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vhl ligand1

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  • Inhibitors & Agonists
    3
    TargetMol | Inhibitors_Agonists
  • PROTAC Products
    3
    TargetMol | PROTAC
(S,R,S)-AHPC hydrochloride
VHL Ligand 1 hydrochloride, ULM-1, Protein degrader 1 hydrochloride
T42071448189-80-7
(S,R,S)-AHPC hydrochloride (Protein degrader 1 hydrochloride) is a building block in the synthesis of proteolysis-targeting chimera technologies (PROTACs).
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(S,R,S)-AHPC
VH032-NH2, MDK7526, VHL ligand 1
T84121448297-52-6
(S,R,S)-AHPC (VH032-NH2) is a VH032-based ligand for recruiting the von Hippel-Lindau (VHL) protein, potentially useful for the targeted degradation of the androgen receptor.
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(S,R,S)-AHPC TFA
VH032-NH2 TFA, VHL ligand 1 TFA
T179271631137-51-3
(S,R,S)-AHPC TFA (VHL ligand 1 TFA) (VH032-NH2 TFA) is a VH032-based ligand designed for von Hippel-Lindau (VHL) protein recruitment. This compound can be linked to protein ligands (e.g., BCR-ABL1) using a linker to create PROTACs (e.g., GMB-475), which effectively induce the degradation of BCR-ABL1, demonstrated by an IC50 of 1.11 μM in Ba F3 cells.
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