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unc9994

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  • Inhibitors & Agonists
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unc9994
UNC-9994, UNC 9994
T290651354030-51-5
UNC9994 is a β-arrestin-biased dopamine D₂ receptor agonist (β-arrestin EC50 = 50 nM; Emax = 97%) with robust in vivo antipsychotic drug-like activities.
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8-10 weeks
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unc9994 hydrochloride
T628532108826-33-9
UNC9994 hydrochloride is a functionally selective, β-arrestin-biased dopamine D2 receptor (D2R) agonist (Ki: 79 nM) that selectively activates β-arrestin recruitment and signal transduction. UNC9994 hydrochloride is a Gi-regulated antagonist of cAMP production and a partial agonist of the D2R β-arrestin-2 interaction, exhibiting psychostimulatory effects.
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8-10 weeks
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