tos peg3

Tos-PEG3, a PEG-based PROTAC linker, is suitable for synthesizing PROTACs and 3'-aminooxy oligonucleotide solid supports[1].

Tos-PEG3-C2-methyl ester is a polyethylene glycol (PEG)-based linker used in the synthesis of PROteolysis TArgeting Chimeras (PROTACs)[1].

Tos-PEG3-CH2COOH is a PEG-based linker for PROTACs that joins two essential ligands, crucial for forming PROTAC molecules, enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Tos-PEG3-O-C1-CH3COO (PROTAC Linker 6) is a PEG-based linker used in the synthesis of PROTACs [1].

Tos-PEG3-NH-Boc (PROTAC Linker 9) is a PEG-based linker used in the synthesis of PROTACs, which connects a target protein with an E3 ubiquitin ligase to promote the target protein's degradation.

Triethylene glycol bis(p-toluenesulfonate) is a polyethylene glycol (PEG) derived linker compound used for synthesizing PROteolysis TArgeting Chimeras (PROTACs)[1].

Tos-PEG3-CH2COOtBu is a PEG-based linker for PROTACs that joins two essential ligands, facilitating selective protein degradation through the ubiquitin-proteasome system within cells.

Tos-PEG3-methyl ester is a PEG linker containing a toluenesulfonyl group and a methyl ester segment. The toluenesulfonyl group serves as an excellent leaving group in nucleophilic substitution reactions. The hydrophilic PEG linker enhances the compound's water solubility. The methyl ester can undergo hydrolysis under strongly basic conditions.

Azide-PEG3-Tos is a PEG-based PROTAC linker used in the synthesis of PROTACs[1], and a non-cleavable 3-unit PEG ADC linker employed in the synthesis of antibody-drug conjugates (ADCs)[2].

m-PEG3-Tos is a PEG-based PROTAC linker used in the synthesis of Silymarin [1].