tobacco alkaloid

beta-Nicotyrine is a tobacco alkaloids Metabolite in the liver.

Anatabine dicitrate, a tobacco alkaloid that can cross the blood-brain barrier, is a potent α4β2 nAChR agonist and inhibits NF-κB activation, thereby reducing amyloid-β (Aβ) production by preventing β-cleavage of the amyloid precursor protein.

Cotinine (NIH-10498) is an alkaloid found in tobacco and is also the predominant metabolite of nicotine.

(R,S)-Anatabine is a minor tobacco alkaloid found in the Solanaceae family of plants, and serves as a specific marker for detecting tobacco use.

Anatabine is a minor tobacco alkaloid with a chemical structural similarity to nicotine. Anatabine is produced in plants of the Solanacea family including tobacco, green tomatoes, peppers, and eggplants. Anatabine is an Aβ inhibitor. (R,S)-Anatabine (tart

Nicotine is a naturally produced alkaloid in the nightshade family of plants (most predominantly in tobacco and Duboisia hopwoodii) and is widely used recreationally as a stimulant and anxiolytic. As a pharmaceutical drug, it is used for smoking cessation to relieve withdrawal symptoms. Nicotine acts as a receptor agonist at most nicotinic acetylcholine receptors (nAChRs), except at two nicotinic receptor subunits (nAChRα9 and nAChRα10) where it acts as a receptor antagonist.

Anabasine ((S)-Anabasine) is an alkaloid extracted from tobacco, acting as a full agonist of nicotinic acetylcholine receptors (nAChRs) with insecticidal activity. It depolarizes TE671 cells that endogenously express human myotypic nAChRs.

Myosmine is a minor tobacco alkaloid that is structurally related to nicotine.

Nicotelline (Nicotellin) is a biomarker and environmental tracer for tobacco smoke particles, a relatively non-volatile alkaloid found in tobacco smoke, and a weak inhibitor of cytochrome P-450 2A6 (CYP2A6). It is used to distinguish tobacco products.

7-Deoxy-trans-dihydronarciclasine is an alkaloid that functions as a tobacco mosaic virus (TMV) inhibitor with an IC50 of 1.80 μM and also serves as an anti-neuroinflammatory agent. This compound reduces Aβ and APP levels in the cerebral cortex of Tg2576 mice [1] [2] [3].

Myosmine-2,4,5,6-d4 is a deuterated compound of Myosmine. Myosmine has a CAS number of 532-12-7. Myosmine is a minor tobacco alkaloid that is structurally related to nicotine.

(S)-(-)-Anatabine ((-)-Anatabine), an alkaloid present in tobacco, is an NRF2 activator that attenuates ovalbumin-induced asthma through oxidative stress and inflammation mitigation as well as up-regulation of Nrf2 HO-1 signaling in rats, and may be used in the study of autoimmune thyroiditis.