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By Target- TGF-beta/Smad
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Results for "
tgfβri-in-3
" in TargetMol Product Catalog- Inhibitors & Agonists2
TGFβRI-IN-3 
T95232763602-67-9
TGFβRI-IN-3 is a highly selective TGFβR1 inhibitor with an IC50 of 0.79 nM and exhibits 2000-fold selectivity against MAP4K4, showing potential applications in immuno-oncology [1].
- $80
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TGFβRI-IN-7
T206870
TGFβRI-IN-7 (compound 16W) is a potent inhibitor of TGFβRI. It effectively inhibits the phosphorylation of SMAD2/3 and reduces the viability of H22 cells, with IC50 values of 12 nM and 65 nM, respectively. In an H22 cell xenograft model, TGFβRI-IN-7 exhibits antitumor efficacy with a TGI of 79.6%.
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