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tenofovir disoproxil

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    7
    TargetMol | Inhibitors_Agonists
Tenofovir Disoproxil
GS 4331, Bis(POC)-PMPA
T7111201341-05-1
Tenofovir Disoproxil (GS 4331) is a nucleotide reverse transcriptase inhibitor to treat HIV and chronic Hepatitis B.
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Tenofovir Disoproxil Fumarate
GS-1278 Disoproxil Fumarate, Tenofovir DF
T2409L202138-50-9
Tenofovir Disoproxil Fumarate (GS-1278 Disoproxil Fumarate) is a pro-drug, fumaric acid salt form of tenofovir, a nucleoside reverse transcriptase inhibitor analog of adenosine. Tenofovir disoproxil fumarate is prescribed to treat HIV and chronic hepatitis B virus (HBV) in adults.
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Tenofovir disoproxil aspartate
CKD-390,CKD390,CKD 390
T289451571075-19-8
Tenofovir disoproxil aspartate, a nucleotide reverse transcriptase inhibitor, is used potentially for the treatment of HBV infection.
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    9-Propenyladenine
    Mutagenic Impurity of Tenofovir Disoproxil,Tenofovir Impurity 2
    T121271446486-33-4
    9-Propenyladenine (9-PA) is a mutagenic impurity in tenofovir disoproxil fumarate (TDF).
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    7-10 days
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    (Z)-9-Propenyladenine
    (Z)-Mutagenic Impurity of Tenofovir Disoproxil
    T134571464851-21-5
    (Z)-9-Propenyladenine is a mutagenic impurity in tenofovir disoproxil fumarate.
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    7-10 days
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    Tenofovir maleate
    T217751236287-04-9
    Tenofovir disoproxil fumarate is a nucleotide reverse transcriptase inhibitor employed in the treatment of HIV and chronic hepatitis B.
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    6-8 weeks
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    Tenofovir diphosphate (sodium salt)
    T37523
    Tenofovir diphosphate is an inhibitor of HIV reverse transcriptase (Kis = 0.022 and 1.55 μM for RNA and DNA, respectively) and hepatitis B virus (HBV) polymerase (Ki = 0.18 μM). It is selective for these enzymes over DNA polymerase α and β, as well as mitochondrial DNA polymerase γ (Kis = 5.2, 81.7, and 59.5 μM, respectively). Tenofovir diphosphate is formed intracellularly through phosphorylation of the prodrugs tenofovir and tenofovir disoproxil by nucleotide kinases. Increased levels of tenofovir diphosphate in isolated peripheral blood mononuclear cells (PBMCs) correlate with a decrease in the risk of simian HIV (SHIV) acquisition in a macaque model of rectal SHIV transmission.
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