tco-nhs ester

TCO-NHS ester is a alkyl/ether-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

TCO-NHS Ester axial is a click chemistry reagent and serves as a building block for amine reactions. It contains a TCO group that undergoes inverse electron demand Diels-Alder (iEDDA) reactions with molecules featuring a Tetrazine group.

(S,E)-TCO-NHS Ester is a Click Amino Acid utilized for labeling amine-containing compounds or biomolecules. The TCO-NHS ester comprises a TCO group, which can undergo an inverse-electron-demand Diels-Alder reaction (iEDDA) with molecules possessing Tetrazine groups.

TCO-PEG4-NHS ester is a PROTAC linker bridge in the PEG class, used for synthesizing various PROTAC molecules. As a cleavable and synthetic ADC, it is also utilized in the synthesis of antibody-drug conjugates (ADCs).

Tetrazine-Ph-PEG5-NHS ester is a PEG-based PROTAC linker that can be used for the synthesis of PROTAC molecules with a tetrazine moiety, which allows click chemistry with molecules containing a TCO moiety.

TCO-PEG12-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

TCO-PEG2-Sulfo-NHS ester is a Polyethylene glycol (PEG)-based linker for PROTAC synthesis[1].

TCO-PEG24-NHS ester is a PEG-based linker for PROTACs that joins two essential ligands, crucial for forming PROTAC molecules, and enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

TCO-PEG3-NHS ester is a PEG-based linker for PROTACs that joins two essential ligands, crucial for PROTAC molecule formation, enabling selective protein degradation via the ubiquitin-proteasome system [in cells].

TCO-PEG6-NHS ester, a PEG-based linker for PROTACs, joins two essential ligands required for the formation of PROTAC molecules, facilitating selective protein degradation by utilizing the (ubiquitin-proteasome system) within cells.

TCO-PEG8-NHS ester is a PEG-based linker for PROTACs that joins two essential ligands, crucial for forming PROTAC molecules, enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

TCO-PEG2-NHS ester is a PROTAC linker categorized within the PEG and Alkyl/ether classes, and it is utilized for synthesizing various PROTAC molecules. As a click chemistry reagent, TCO-PEG2-NHS ester contains a TCO group that can engage in an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing a Tetrazine group.

TCO-PEG5-NHS ester is a PROTAC linker belonging to the PEG and Alkyl/ether categories, used for synthesizing various PROTAC molecules. This click chemistry reagent features a TCO group, enabling it to undergo an inverse electron-demand Diels-Alder reaction (iEDDA) with molecules containing a Tetrazine group.

TCO-PEG2-Sulfo-NHS ester sodium is a PROTAC linker from the PEG category, utilized in the synthesis of PROTAC molecules.

(E)-TCO-PEG4-NHS ester is a PEG-based linker for PROTACs that connects two essential ligands, facilitating the formation of PROTAC molecules and enabling selective protein degradation via the ubiquitin-proteasome system within cells.

TCO-GK-PEG4-NHS ester serves as an ADC linker, suitable for synthesizing [18F] AlF-NOTA-Tz-TCO-GK-2Rs15d, which demonstrates high affinity and immunoreactivity to HER2 [1]. This compound is a click chemistry reagent containing a TCO group that can engage in an inverse electron demand Diels-Alder reaction (iEDDA) with Tetrazine-containing molecules.

(S)-TCO-PEG4-NHS ester, an ADC linker with four PEG units, utilizes its TCO group to facilitate an inverse electron demand Diels-Alder reaction (iEDDA) with Tetrazine-containing molecules.

(S)-TCO-PEG8-NHS ester, an ADC linker featuring 8 PEG units, actively employs its TCO group to facilitate an inverse electron demand Diels-Alder reaction (iEDDA) with molecules possessing Tetrazine groups.

(R)-TCO-PEG8-NHS ester, an ADC linker featuring 8 polyethylene glycol (PEG) units, utilizes its TCO group to engage in an inverse electron demand Diels-Alder reaction (iEDDA) with Tetrazine-containing molecules.

TCO-PEG4-TFP ester is an amine-reactive labeling reagent used for the modification of proteins, antibodies, and other amine-containing biopolymers. TFP is a reactive ester that demonstrates superior stability during hydrolysis in aqueous media, enhancing the efficiency and reproducibility of biopolymer labeling. The TFP ester of carboxylic acid reacts with primary amines at a rate equivalent to NHS esters, forming a covalent amide bond identical to that produced by the reaction of primary amines with NHS or sulfo-NHS esters.

(S,E)-TCO2-PEG3-NHS ester is reactive to NH2 groups and is employed in chemical synthesis. It includes a TCO group that can undergo a specific "click" reaction with tetrazine groups.

Methyltetrazine-PEG12-NHS ester is a click chemistry reagent that contains an azide group. It reacts with compounds containing TCO to form a stable covalent bond.