taurolithocholic acid 3 sulfate (sodium salt)

Taurolithocholic Acid 3-sulfate sodium salt is a GPR39 agonist. In the absence of Zn²⁺, its EC50 values are 71.6 μM and 69.4 μM in M39-20 and hGPR39-2 cells, respectively; in the presence of Zn²⁺, the values are 9 μM and 9.6 μM, respectively. Taurolithocholic Acid 3-sulfate sodium salt activates the GPR39 receptor and mediates intracellular calcium signaling pathways independently of the Zn²⁺-binding sites H17 and H19, and can be used in research on gallbladder-related diseases.

Taurolithocholic Acid 3-sulfate (sodium salt) (Standard) is a reference standard for research and analysis in studies involving Taurolithocholic Acid 3-sulfate (sodium salt). Taurolithocholic acid 3-sulfate (TLCA3S) is a metabolite of the conjugated bile acid taurolithocholic acid . TLCA3S has been used to study bile acid transport in cellular models and to induce pancreatitis in mouse models of bile acid infusion pancreatitis.

Taurolithocholic Acid-[D4]-3-Sulfate Sodium Salt (Standard) is a reference standard of Taurolithocholic Acid-[D4]-3-Sulfate Sodium Salt intended for quantitative analysis, quality control, and related biochemical research applications.