sterol 14α-demethylase

(Rac)-Ketoconazole ((Rac)-R 41400) is an orally active antifungal imidazole compound. It inhibits ergosterol synthesis in fungi by targeting the cytochrome P450-dependent enzyme, 14α-sterol demethylase (CYP51), on the fungal cell membrane. This disruption leads to dysfunction of the cell membrane, ultimately hindering fungal growth and proliferation. (Rac)-Ketoconazole is applicable in studying fungal infections.

CYP51-IN-24 (Compound 22) is an inhibitor of Sterol 14α-Demethylase (CYP51). It exhibits potent inhibitory activity against both wild-type and resistant fungi. By binding to the fungal CYP51 enzyme, CYP51-IN-24 prevents the biosynthesis of ergosterol. This compound is applicable in the research and development of treatments for drug-resistant fungal infections.

Pyrisoxazole is a novel fungicide inhibitor of Sterol 14α-demethylase.

Pyrisoxazole (Standard) is the standard substance of Pyrisoxazole, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Pyrisoxazole is a novel fungicide inhibitor of Sterol 14α-demethylase.