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By Target- Sodium Channel
- Stearoyl-CoA Desaturase (SCD)(1)
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Results for "
slc13a5 in 1
" in TargetMol Product Catalog- Inhibitors & Agonists2
SLC13A5-IN-1
T129312227548-95-8
SLC13A5-IN-1 is a selective inhibitor of the sodium-citrate co-transporter (SLC13A5) that completely blocks the uptake of 14C-citrate, with an IC50 of 0.022 μM in HepG2 cells.
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LBA-3
T868032918263-09-7
LBA-3, a selective and orally active inhibitor of the sodium-coupled citrate transporter SLC13A5, exhibits an IC50 of 67 nM. This compound effectively reduces triglyceride and total cholesterol levels in both oleic and palmitic acid (OPA)-stimulated AML12 cells and PCN-stimulated primary mouse hepatocytes, as well as in mouse models, without showing detectable toxicity. Additionally, LBA-3 is permeable to the blood-brain barrier [1].
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