selenium

L-SelenoMethionine (L-(+)-Selenomethionine) is a naturally occurring amino acid. It promotes cell cycle progression and elevates the expression of the antioxidant enzymes thioredoxin reductase, glutathione reductase.

Selenium sulfide has antimicrobial activity and is commonly used to control dandruff, seborrheic dermatitis and psoriasis.

DL-Selenomethionine (Seleno-DL-methionine) is a selenium (Se) analogue of methionine in which sulfur is replaced with the trace element selenium. Selenomethionine (SeMet) can incorporate into proteins in place of methionine with no effects on protein structure and function, providing a mechanism for reversible Se storage in organs and tissues.

Se2h is a cruzain inhibitor exhibiting potent activity against intracellular amastigotes of Trypanosoma cruzi (EC50< 1 μM, SI> 10), with an inhibitory effect on cruzain of IC50< 100 nM (SI> 5.55). Compared to Benznidazole and cruzain inhibitor K777, Se2h shows superior selectivity and inhibition while its selenazole structure reduces selenium-related toxicity. Se2h demonstrates antiparasitic activity and holds promise for Chagas disease research.

Piaselenole could determine the traces of selenium.

Se-DOPE is a selenium-containing phospholipid molecule utilized for the synthesis of bifunctional Janus lipase. It facilitates the production of ROS under light induction and scavenges ROS in the presence of glutathione. Se-DOPE plays a role in regulating redox and immune homeostasis, aiding in the healing of infectious diabetic wounds.

Manganese carbonyl is used in organometallic reactions to prepare polynuclear selenium manganese carbonyl cluster complexes.

Antibacterialagent 282 (Compound CP7) is a selenium-containing derivative of Ciprofloxacin that serves as an antibacterial agent. It exhibits significant activity against both Gram-positive and Gram-negative bacteria, with MICs ranging from 0.1-1.56 μg/mL and 0.1-3.13 μg/mL, respectively (MBCs are 0.2-1.56 μg/mL and 0.39-12.5 μg/mL). Additionally, Antibacterialagent 282 effectively disrupts and prevents P. aeruginosa biofilm formation and significantly inhibits the DNA gyrase of E. coli.

Selenohomolysine is a selenium-containing amino acid.

Selenolanthionine is the major water-soluble selenium compound in the selenium tolerant plant Cardamine violifolia.

DHU-Se1 is a potent anti-inflammatory agent that stimulates the release of reactive selenium compounds from macrophages and reduces the expression of cellular inflammatory factors such as iNOS and TNF-α. Additionally, DHU-Se1 blocks the polarization of macrophages from M0 to M1, thereby alleviating the inflammatory process.

Ptaquiloside shows genotoxicity, it also has carcinogenic effects. Ptaquiloside has immunosuppressive effects, it reduces NK cell activities by enhancing metallothionein expression, which is prevented by selenium.

SeGalNac, a selenium metabolite present in human urine, can be utilized in the study of selenoglucose metabolism [1] [2].

Sodium butane-1-sulfonate (Sodium 1-butanesulfonate) can be used as a mobile phase for the separation of arsenic or selenium compounds.

Sodium selenide is a valuable selenization reagent in organic synthesis, aiding the introduction of selenium groups into a variety of organic substrates, such as alkenes, alkynes, and carbonyl compounds. It plays a crucial role in synthesizing organoselenium compounds, which are used in various organic reactions.