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Results for "
sar247799
" in TargetMol Product Catalog- Inhibitors & Agonists1
SAR247799
SAR 247799, S1P1 agonist 3
T387161315311-14-8
SAR247799 (S1P1 agonist 3) is a selective and G-protein-biased S1P1 agonist that activates downstream G-protein signaling pathways more preferentially than β-blocker proteins and internalized signaling pathways, activates S1P 1 on endothelial cells without causing receptor desensitization, and protects the endothelium without affecting lymphocyte populations, and can be used to study type 2 diabetes, endothelial dysfunction and vascular hyperpermeability.
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