s (5' adenosyl) l methionine chloride

S-(5'-Adenosyl)-L-methionine chloride is a natural product. The catalog number is TN6669 and the CAS number is 24346-00-7. S-(5'-Adenosyl)-L-methionine chloride can be used as a reference standard.

SAHO is a catechol‑O‑methyltransferase (COMT) inhibitor with an IC50 value of 860 μM, and can be used in research related to methylation reaction regulators.

SAHO2is a sulfone form of the methyl donor S-(5'-adenosyl)-L-methionine chloride and is a substrate for radical SAM enzymes.1It is reductively cleaved to 5'-deoxyadenosine and 5'-thioadenosine sulfinic acid by the radical SAM enzymes NosL or NosN. 1.Mandalapu, D., Ji, X., and Zhang, Q.Reductive cleavage of sulfoxide and sulfone by two radical S-adenosyl-L-methionine enzymesBiochemistry58(1)36-39(2019)

Nε,Nε,Nε-Trimethyllysine chloride (Lys(Me)3-OH Chloride) is a methylated derivative of lysine, found in histone proteins and serves as a coenzyme in fatty acid oxidation. It is a precursor for carnitine, generated by S-adenosyl-L-methionine on lysine residues. Upon proteolysis, it is converted to 3-hydroxy-6-N-trimethyllysine by mitochondrial 6-N-trimethyllysine dioxygenase, initiating carnitine biosynthesis.