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Results for "
ruski 43 hydrochloride
" in TargetMol Product Catalog- Inhibitors & Agonists1
RU-SKI 43 hydrochloride
T12797L1782573-67-4
RU-SKI 43 hydrochloride is a potent and selective inhibitor of Hedgehog acyltransferase (Hhat) with an IC50 of 850 nM and exhibits anti-cancer activity.
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RUSKI 43
T127971043797-53-0In house
RU-SKI 43 is a potent and selective hedgehog acyltransferase (Hhat) inhibitor with an IC50 of 850 nM. It exhibits anticancer activity and is a potential treatment for lung adenocarcinomas. RU-SKI 43 reduces Gli-1 activation through smoothening-independent non-canonical signaling and inhibits Akt and mTOR pathway activity.
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