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(2)
By Target- COX
- Cannabinoid Receptor(1)
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By Target By ResearchField- Cancer(2)
- Inflammation(2)
- Immune System(1)
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Results for "
rofecoxib
" in TargetMol Product Catalog.- Inhibitors & Agonists3
- Compound Libraries1
- Isotope Products1
- Reference Standards1
Rofecoxib
MK-0966, MK 966
T1185162011-90-7
Rofecoxib (MK 966) binds to and inhibits the enzyme cyclooxygenase-2 (COX-2), resulting in an inhibition of the conversion of arachidonic acid to prostaglandins. Rofecoxib is a synthetic, nonsteroidal derivative of phenyl-furanone with anti-inflammatory, antipyretic and analgesic properties and potential antineoplastic properties. COX-related metabolic pathways may represent key regulators of cell proliferation and neo-angiogenesis. Some epithelial tumor cell types overexpress pro-angiogenic COX-2.
- $30
Size
QTY
Rofecoxib-[D5] (Standard)
TMSM-6406544684-93-7
Rofecoxib-[D5] (Standard) is a reference standard of Rofecoxib-[D5] intended for quantitative analysis, quality control, and related biochemical research applications.
- $898
Size
QTY
Parecoxib sodium
SC-69124A, SC69124A, SC 69124A, Dynastat
T1780L198470-85-8
Parecoxib sodium is a prodrug of Valdecoxib and a selective, orally active COX-2 inhibitor that suppresses prostaglandin (PG) synthesis and alleviates pain and inflammation. Parecoxib sodium also acts as a cannabinoid 1 (CB1) receptor agonist (EC50=2.4 µM).
- $30
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