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rmc-5552

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  • Inhibitors & Agonists
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RMC-5552
T360892382768-62-7
RMC-5552 is a potent and selective mTORC1 inhibitor, effectively inhibiting phosphorylation of mTORC1 pS6K and p4EBP1 with IC50s of 0.14 nM and 0.48 nM, respectively [RMC-5552]. The compound exhibits significant anti-cancer activity.
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7-10 days
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(32-Carbonyl)-RMC-5552
T399582382768-55-8
(32-Carbonyl)-RMC-5552 is a highly effective mTOR inhibitor, inhibiting both mTORC1 and mTORC2 substrate phosphorylation. It significantly suppresses the phosphorylation of p-P70S6K-(T389), p-4E-BP1-(T37 36), and p-AKT1 2 3-(S473) with pIC50 values >9, >9, and 8~9, respectively.
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