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rgat-2

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  • Inhibitors & Agonists
    2
    TargetMol | Inhibitors_Agonists
(S)-SNAP5114
T16831157604-55-2
(S)-SNAP5114 is a selective inhibitor of GABA transport, exhibiting IC50 values of 5 μM for hGAT-3 and 21 μM for rGAT-2, and possesses anticonvulsant properties.
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6-8 weeks
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TargetMol | Inhibitor Sale
SKF89976A HCl
T6855085375-85-5
SKF89976A is a potent GABA uptake inhibitor, which is selective for GAT-1 (IC50 values are 0.13, 550, 944 and 7210 μM for hGAT-1, rGAT-2, hGAT-3 and hBGT-1 respectively). SKF89976A inhibits transport current competitively (Ki = 7 μM) and transmitter-gated current non-competitively (Ki = 0.03 nM). It is able to pass the blood-brain barrier after systemic administration and is active in vivo.
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1-2 weeks
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