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Search Result

Search Results for " remodeling "

Targets

5-HT Receptor

30

Compounds

3

Natural Products

216

Recombinant Proteins

2

Libraries

Cat No. Product Name Synonyms Targets
T23312 SB 204741 5-HT Receptor
SB 204741 is a 5-HT2B receptor antagonist.
T9765 TJ-M2010-5 MyD88
TJ-M2010-5 is a MyD88 inhibitor that binds to the TIR domain to interfere with its homodimerization and suppress MyD88 signaling. TJ-M2010-5 can be used in myocardial ischemia/reperfusion injury studies.
T11394 GFB-8438 TRP/TRPV Channel
GFB-8438 is a potent and subtype selective inhibitor of TRPC5(IC50s of 0.18 and 0.29 μM of hTRPC5 and hTRPC4, respectively).
T15418 GS-6201 CVT-6883 Adenosine Receptor
GS-6201 (CVT-6883) is a selective antagonist of adenosine A2B receptor. GS-6201 shows high affinity and selectivity for the human adenosine A2B receptors with a Ki of 22 nM.
T5443 JQ-1 (carboxylic acid) JQ-1 carboxylic acid Epigenetic Reader Domain
JQ-1 (carboxylic acid) is a cell-permeable BRD4 inhibitor with IC50s of 77 nM for BRD4(1) and 33 nM for BRD4(2)
T24115 GSK854 GSK-854,GSK 854 Apoptosis
GSK854 is a highly selective and potent inhibitor of troponin I interacting kinase (TNNI3K) that inhibits myocardial infarction-injured cellular pyroptosis and apoptosis in mice, which may limit oxidative stress, injury,...
T13360 XRK3F2 Autophagy
XRK3F2 is an inhibitor of the p62-ZZ domain, blunts MM-induced Runx2 suppression in vitro, and induces new bone formation and remodeling in the presence of tumor in vivo.
T77617 MMP-9-IN-6 MMP
MMP-9-IN-6 is an MMP-9 inhibitor with an IC50 value of 50 μM and good anti-ulcer efficacy.MMP-9-IN-6 has potential anti-tumor activity and can be used to study tissue remodeling, wound repair and atherosclerosis.
T9566 PY-60 Annexin A , YAP
PY-60 potently activates YAP transcriptional activities targeting annexin A2 (Kd = 1.4 µM). PY-60 activates a proproliferative, YAP-dependent transcriptional program in the adult animal capable of remodeling the epidermi...
T12721 Rho-Kinase-IN-1 ROCK
Rho-Kinase-IN-1 is an inhibitor of ROCK with Kis of 30.5 nM and 3.9 nM for ROCK1 and ROCK2, respectively. Rho-Kinase-IN-1 can be used in studies about excessive cell proliferation, remodeling, edema and inflammation dise...
T21632 Myoseverin Others , Microtubule Associated
Myoseverin, an inducer of the reversible fission of multinucleated myotubes into mononucleated fragments, affecting the expression of a variety of growth factor, immunomodulatory, extracellular matrix-remodeling, and str...
T2129 Zaprinast PDE
Zaprinast is a cGMP-selective phosphodiesterase (PDE) inhibitor and a GPR35 agonist. It has a strong activating effect on rat GPR35 and a certain activating effect on human GPR35. It reduces vascular remodeling through a...
T3661 Citarinostat ACY241,HDAC-IN-2 HDAC
ACY-241, also known as Citarinostat (ACY241), is a potent, selective and orally available histone deacetylase (HDAC) inhibitor, with potential antineoplastic activity. Upon oral administration, ACY-241 inhibits the activ...
T3712 Mivebresib ABBV-075 Apoptosis , Epigenetic Reader Domain
Mivebresib (ABBV-075), also known as ABBV-075, is a potent BET inhibitor (bromodomain (BRD)-containing protein) with potential antineoplastic activity. Upon administration, the bromodomain inhibitor ABBV-075 binds to the...
T28222 5-Hydroxy-1-methylhydantoin HD-003,HD003,NZ419,NZ-419,HD 003,NZ 419 Bradykinin Receptor
5-Hydroxy-1-methylhydantoin (HD-003) is an antioxidant potentially for the treatment of renal failure. A creatinine metabolite, 5-Hydroxy-1-methylhydantoin , a hydroxyl radical scavenger, has previously been shown to con...
T19472 Nedocromil sodium Nedocromil disodium salt,FPL 59002KP Others
Nedocromil sodium is a pharmacologic stabilizer of mast cells, has been shown to normalize cytokine levels and attenuate cardiac remodeling.
T28005 MDL-100240
MDL-100240 is a dual inhibitor of angiotensin-converting enzyme (ACE) and neprilysin with a balanced activity. MDL 100240 shows an impressive effectiveness both in preventing and in regressing hypertension-induced vascul...
T28469 PT-262 PT 262
PT-262 is a ROCK (Rho-associated coiled-coil forming protein kinase) inhibitor. It induces cytoskeleton remodeling and migration inhibition in lung carcinoma cells.
T82308 GLP-2 (1-34) (human)
GLP-2 (1-34) (human), a polypeptide secreted from the intestine shortly after eating, is utilized in research related to bone remodeling processes [1].
T39829 BPK-25
BPK-25 is an active acrylamide compound that enhances the degradation of proteins in the nucleosome remodeling and deacetylation (NuRD) complex through a post-translational mechanism involving covalent protein interactio...
T36763 PAF C-18
PAF C-18 is a naturally occurring phospholipid produced upon stimulation through two distinct pathways known as the remodeling" and 'de novo' pathways. It is less potent than PAF C-16 in the induction of platelet aggrega...
T61344 VO-OHPic
VO-OHPic is a reversible, noncompetitive, and selective inhibitor of PTEN with an IC50 of 46 nM. It effectively attenuates apoptosis, adverse cardiac remodeling, and the presence of pro-inflammatory M1 macrophages in mod...
T37268 PAF C-16 Carboxylic Acid
PAF C-16 is a naturally occurring phospholipid produced upon stimulation through two distinct pathways known as the remodeling" and 'de novo' pathways. It is a potent mediator of neutrophil migration and the production o...
T39785 TH5427 hydrochloride
TH5427 hydrochloride is a potent and selective inhibitor of NUDT5 with an IC50 of 29 nM. It demonstrates a remarkable 690-fold selectivity towards NUDT5 compared to MTH1. Moreover, TH5427 hydrochloride effectively inhibi...
T70210 FT-1101 free base
FT-1101 is an orally bioavailable, potent and selective BET inhibitor. FT-1101 binds to the acetylated lysine recognition motifs in the bromodomain sites of BET proteins, thereby preventing the interaction between the B...
T70748 Bisthianostat
Bisthianostat, also known as CF367 or CF367;-C, is a novel Orally Efficacious Pan-HDAC Inhibitor. Bisthianostat selectively binds to and inhibits HDACs, which inhibits deacetylation of histone proteins and leads to the a...
T36838 (R)-Bromoenol lactone
The phospholipases are an extensive family of lipid hydrolases that function in cell signaling, digestion, membrane remodeling, and as venom components. The calcium-independent phospholipases (iPLA2) are a PLA2 subfamily...
T80130 SDF-1α (human) CXCR
SDF-1α (human) serves as a chemotactic agent for mononuclear cells through its interaction with the CXCR4 receptor, facilitating critical biological processes such as stem cell homing, retention, survival, and proliferat...
T71110 Nanatinostat TFA
Nanatinostat, also known as Tractinostat, CHR-3996 and VRx-3996, is an orally bioavailable, second-generation hydroxamic acid-based inhibitor of histone deacetylase (HDAC) with potential antineoplastic activity. HDAC inh...
T35598 Neuromedin U-25 (human) (trifluoroacetate salt)
Neuromedin U (NMU) is a neuropeptide first demonstrated to drive smooth muscle contraction.1Translated as a 174 amino acid propeptide, NMU is cleaved to different lengths in different animals. It has diverse receptor-med...

Compounds

SB 204741
T23312
Synonym:
Target: 5-HT Receptor
TJ-M2010-5
T9765
Synonym:
Target: MyD88
GFB-8438
T11394
Synonym:
Target: TRP/TRPV Channel
GS-6201
T15418
Synonym: CVT-6883
Target: Adenosine Receptor
JQ-1 (carboxylic acid)
T5443
Synonym: JQ-1 carboxylic acid
Target: Epigenetic Reader Domain
GSK854
T24115
Synonym: GSK-854,GSK 854
Target: Apoptosis
XRK3F2
T13360
Synonym:
Target: Autophagy
MMP-9-IN-6
T77617
Synonym:
Target: MMP
PY-60
T9566
Synonym:
Target: Annexin A, YAP
Rho-Kinase-IN-1
T12721
Synonym:
Target: ROCK
Myoseverin
T21632
Synonym:
Target: Others, Microtubule Associated
Zaprinast
T2129
Synonym:
Target: PDE
Citarinostat
T3661
Synonym: ACY241,HDAC-IN-2
Target: HDAC
Mivebresib
T3712
Synonym: ABBV-075
Target: Apoptosis, Epigenetic Reader Domain
5-Hydroxy-1-methylhydantoin
T28222
Synonym: HD-003,HD003,NZ419,NZ-419,HD 003,NZ 419
Target: Bradykinin Receptor
Nedocromil sodium
T19472
Synonym: Nedocromil disodium salt,FPL 59002KP
Target: Others
MDL-100240
T28005
Synonym:
Target:
PT-262
T28469
Synonym: PT 262
Target:
GLP-2 (1-34) (human)
T82308
Synonym:
Target:
BPK-25
T39829
Synonym:
Target:
PAF C-18
T36763
Synonym:
Target:
VO-OHPic
T61344
Synonym:
Target:
PAF C-16 Carboxylic Acid
T37268
Synonym:
Target:
TH5427 hydrochloride
T39785
Synonym:
Target:
FT-1101 free base
T70210
Synonym:
Target:
Bisthianostat
T70748
Synonym:
Target:
(R)-Bromoenol lactone
T36838
Synonym:
Target:
SDF-1α (human)
T80130
Synonym:
Target: CXCR
Nanatinostat TFA
T71110
Synonym:
Target:
Neuromedin U-25 (human) (trifluoroacetate salt)
T35598
Synonym:
Target:
Cat No. Product Name Synonyms Targets
T0543 7-Methylxanthine Heteroxanthine,Heteroxanthin Nucleoside Antimetabolite/Analog , Endogenous Metabolite
7-Methylxanthine (Heteroxanthine), a methyl derivative of xanthine, is one of the purine components in urinary calculi. 7-Methylxanthine appears to prevent FDM in pigmented rabbits by remodeling the posterior sclera.
T20089 ATP Atipi,ATP disodium salt hydrate,Triphosphoric acid adenosine ester,Ara-ATP,Triphosphaden,Adenosine triphosphate;Ara-ATP,Adenosine triphosphate Endogenous Metabolite
ATP (Adenosine triphosphate) provides cellular energy, participates in overall energy balance, and maintains intracellular homeostasis. ATP can act as an extracellular signaling molecule through interactions with specifi...
TN4819 (-)-Praeruptorin A ATPase , IL Receptor , Calcium Channel , P-gp
(-)-Praeruptorin A has anti-inflammatory, anti-contractile and anti-hyperplasia activities, it exerts distinct relaxant effects on isolated rat aorta rings dependent on endothelium and nitric oxide synthesis;it also can ...

Natural Products

7-Methylxanthine
T0543
Synonym: Heteroxanthine,Heteroxanthin
Target: Nucleoside Antimetabolite/Analog, Endogenous Metabolite
ATP
T20089
Synonym: Atipi,ATP disodium salt hydrate,Triphosphoric acid adenosine ester,Ara-ATP,Triphosphaden,Adenosine triphosphate;Ara-ATP,Adenosine triphosphate
Target: Endogenous Metabolite
(-)-Praeruptorin A
TN4819
Synonym:
Target: ATPase, IL Receptor, Calcium Channel, P-gp

Recombinant Proteins

Species：
Human (121)
Mouse (53)
Rat (18)
Cynomolgus (8)
Rhesus (3)
Bovine (2)
Canine (2)
CHIKV (1)
Chicken (1)
E. coli (1)
Expression System：
HEK293 (116)
E. coli (65)
Baculovirus-Insect Cells (17)
Human Cells (9)
Yeast (4)
Baculovirus (2)
CHO (2)
in vitro E. coli expression system (1)
Tag：
His (74)
hFc (31)
N-terminal 6xHis-tagged (28)
Tag Free (19)
C-6His (10)
His,GST (9)
N-terminal 6xHis-SUMO-tagged (8)
N-terminal 10xHis-tagged and C-terminal Myc-tagged (6)
C-His (3)
His,hFc (3)
Cat No. Product Name Species Expression System
TMPJ-00242 PARVA Protein, Human, Recombinant (His) Human E. coli
Alpha-Parvin (PARVA) is a member of the Parvin family. PARVA contains two CH (calponin-homology) domains. PARVA is widely expressed, with highest levels in heart, skeletal muscle, kidney and liver. PARVA interacts with i...
TMPH-01029 CAPN1 Protein, Human, Recombinant (His) Human E. coli
Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Proteolytically cleaves CTBP1 at 'Asn-375', 'Gly-387' and 'His...
TMPY-00117 FGF-16 Protein, Human, Cynomolgus, Recombinant Human,Cynomolgus Baculovirus-Insect Cells
Fibroblast growth factor 16 (FGF16) is preferentially expressed in the heart after birth, suggesting its regulation is associated with tissue-specific chromatin remodeling and DNA-protein interactions. Mutation of the ME...
TMPH-01031 CAPN2 Protein, Human, Recombinant (His) Human E. coli
Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Proteolytically cleaves MYOC at 'Arg-226'. Proteolytically cle...
TMPY-04142 RANK/TNFRSF11A Protein, Human, Recombinant (hFc) Human HEK293
TNFRSF11A is a member of the TNF-receptor superfamily. In mouse, it is also known as CD265. TNFRSF11A contains 4 TNFR-Cys repeats and is widely expressed with high levels in skeletal muscle, thymus, liver, colon, small i...
TMPY-02785 Tetranectin Protein, Mouse, Recombinant (His) Mouse HEK293
Tetranectin (TN), also known as C-type lectin domain family 3, member B (CLEC3B) is a member of the C-type lectin Family. It is plasminogen kringle 4 binding protein and regulates fibrinolysis and proteolytic processes v...
TMPY-00925 SOST Protein, Human, Recombinant (His) Human HEK293
Sclerostin, the protein product of the SOST gene, is a potent inhibitor of bone formation. Sclerostin protein is widely expressed at low levels with highest levels in bone, cartilage, kidney, liver, bone marrow and prima...
TMPY-01633 SOST Protein, Rat, Recombinant (His) Rat HEK293
Sclerostin, the protein product of the SOST gene, is a potent inhibitor of bone formation. Sclerostin protein is widely expressed at low levels with highest levels in bone, cartilage, kidney, liver, bone marrow and prima...
TMPY-00888 MMP-9 Protein, Human, Recombinant (His) Human HEK293
Matrix metalloproteinases (MMPs) are neutral proteinases that are involved in the breakdown and remodeling of the extracellular matrix (ECM) under a variety of physiological and pathological conditions, such as morphogen...
TMPY-01248 MMP-9 Protein, Human, Recombinant Human HEK293
Matrix metalloproteinases (MMPs) are neutral proteinases that are involved in the breakdown and remodeling of the extracellular matrix (ECM) under a variety of physiological and pathological conditions, such as morphogen...
TMPY-01919 MMP-9 Protein, Mouse, Recombinant Mouse HEK293
Matrix metalloproteinases (MMPs) are neutral proteinases that are involved in the breakdown and remodeling of the extracellular matrix (ECM) under a variety of physiological and pathological conditions, such as morphogen...
TMPY-00210 FGF-2 Protein, Mouse, Recombinant (His) Mouse E. coli
Basic fibroblast growth factor (bFGF), also known as FGF2, is a member of the fibroblast growth factor (FGF) family. It is a highly specific chemotactic and mitogenic factor for many cell types, appears to be involved in...
TMPY-02869 MMP-12 Protein, Human, Recombinant (catalytic domain) Human E. coli
Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases that degrade components of the extracellular matrix (ECM) and play essential roles in various physiological processes such as morphogenesis, ...
TMPY-00749 FGF-2 Protein, Human, Recombinant Human E. coli
Basic fibroblast growth factor (bFGF), also known as FGF2, is a member of the fibroblast growth factor (FGF) family. It is a highly specific chemotactic and mitogenic factor for many cell types, appears to be involved in...
TMPY-01064 TIE2 Protein, Human, Recombinant (His) Human HEK293
TEK, or TIE-2, is an endothelial cell-specific receptor tyrosine kinase (RTK) that is known as a functioning molecule of vascular endothelial cells. TEK comprises a subfamily of RTK with TIE, and these two receptors play...
TMPY-00930 TIE2 Protein, Human, Recombinant (His & hFc) Human HEK293
TEK, or TIE-2, is an endothelial cell-specific receptor tyrosine kinase (RTK) that is known as a functioning molecule of vascular endothelial cells. TEK comprises a subfamily of RTK with TIE, and these two receptors play...
TMPY-01786 EphB4 Protein, Mouse, Recombinant (hFc) Mouse HEK293
Ephrin type-B receptor 4 is a protein that in humans is encoded by the EPHB4 gene. It is a single-pass type I membrane protein belonging to the ephrin receptor subfamily of protein kinase superfamily. Members of the ephr...
TMPJ-00662 RANKL/TNFSF11/CD254 Protein, Human, Recombinant (E. coli) Human E. coli
CD254, also known as RANKL, TNFSF11, TRANCE, OPGL and ODF, is a type II membrane protein of the tumor necrosis factor (TNF) superfamily, and affects the immune system and control bone regeneration and remodeling. RANKL i...
TMPY-01395 CTHRC1 Protein, Human, Recombinant (His) Human HEK293
Collagen triple helix repeat-containing protein 1, also known as Protein NMTC1, and CTHRC1, is a secreted protein that is glycosylated and highly conserved from lower chordates to mammals. CTHRC1 expression was not detec...
TMPY-01884 MMP-8 Protein, Human, Recombinant Human HEK293
Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases that degrade components of the extracellular matrix (ECM) and play essential roles in various physiological processes such as morphogenesis, ...
TMPY-03014 Osteoactivin/GPNMB Protein, Mouse, Recombinant (His) Mouse HEK293
GPNMB belongs to the PMEL / NMB family, also known as Osteoactivin and Hematopoietic growth factor-inducible neurokinin 1 ( HGFIN ), is a transmembrane glycoprotein that is expressed in numerous cells, including osteocla...
TMPY-01478 HSP90 alpha Protein, Human, Recombinant Human E. coli
Heat shock protein 90 (90 kDa heat-shock protein, HSP90) is a molecular chaperone involved in the trafficking of proteins in the cell. It is a remarkably versatile protein involved in the stress response and normal homoe...
TMPY-04976 PDGFC Protein, Mouse, Recombinant (His) Mouse Yeast
PDGF-C is a member of the PDGF/VEGF family of growth factors with a unique domain organization and expression pattern. Platelet-derived growth factor receptors (PDGFRs) are catalytic receptors that have intracellular tyr...
TMPY-00978 Progranulin Protein, Human, Recombinant (His) Human HEK293
Granulins are a family of secreted, glycosylated peptides that are cleaved from a single precursor protein with 7.5 repeats of a highly conserved 12-cysteine granulin/epithelin motif. The precursor protein, progranulin, ...
TMPY-03674 RANKL/TNFSF11/CD254 Protein, Human, Recombinant (mFc) Human HEK293
Tumor necrosis factor ligand superfamily member 11, also known as Receptor activator of nuclear factor kappa-B ligand, Osteoprotegerin ligand, TNFSF11, RANKL, TRANCE, OPGL and CD254, is a single-pass type II membrane pro...
TMPY-02726 RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (hFc) Mouse HEK293
Tumor necrosis factor ligand superfamily member 11, also known as Receptor activator of nuclear factor kappa-B ligand, Osteoprotegerin ligand, TNFSF11, RANKL, TRANCE, OPGL and CD254, is a single-pass type II membrane pro...
TMPY-02154 FAP Protein, Human, Recombinant (His) Human HEK293
Seprase, also known as 17 kDa melanoma membrane-bound gelatinase , Fibroblast activation protein alpha, Integral membrane serine protease and FAP, is a single-pass type II membrane protein which belongs to thepeptidase S...
TMPY-03364 RANKL/TNFSF11/CD254 Protein, Human, Recombinant Human HEK293
Tumor necrosis factor ligand superfamily member 11, also known as Receptor activator of nuclear factor kappa-B ligand, Osteoprotegerin ligand, TNFSF11, RANKL, TRANCE, OPGL and CD254, is a single-pass type II membrane pro...
TMPY-02638 TGF beta 1 Protein, Human/Rhesus/Cynomolgus/Canine, Recombinant Human,Rhesus,Cynomolgus,Canine CHO
TGF-beta 1 is a member of the transforming growth factor beta (TGF-beta) family. The transforming growth factor-beta family of polypeptides are involved in the regulation of cellular processes, including cell division, d...
TMPY-02590 HMGB1 Protein, Mouse, Recombinant (hFc) Mouse HEK293
High-mobility group box 1 protein (HMGB1), also known as HMG-1 or amphoterin previously, is a member of the HMGB family consisting of three members, HMGB1, HMGB2, and HMGB3. HMGB1 is a DNA-binding nuclear protein, releas...
TMPY-01133 Latent TGF beta 1 Protein, Human, Recombinant (His) Human HEK293
TGF-beta 1 is a member of the transforming growth factor beta (TGF-beta) family. The transforming growth factor-beta family of polypeptides are involved in the regulation of cellular processes, including cell division, d...
TMPY-00500 Latent TGF beta 1 Protein, Mouse, Recombinant (His) Mouse HEK293
TGF-beta 1 is a member of the transforming growth factor beta (TGF-beta) family. The transforming growth factor-beta family of polypeptides are involved in the regulation of cellular processes, including cell division, d...
TMPY-01848 HMGB1 Protein, Human, Recombinant (aa 1-215, His) Human HEK293
High-mobility group box 1 protein (HMGB1), also known as HMG-1 or amphoterin previously, is a member of the HMGB family consisting of three members, HMGB1, HMGB2, and HMGB3. HMGB1 is a DNA-binding nuclear protein, releas...
TMPY-04962 FAP Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293
Seprase, also known as 17 kDa melanoma membrane-bound gelatinase , Fibroblast activation protein alpha, Integral membrane serine protease and FAP, is a single-pass type II membrane protein which belongs to thepeptidase S...
TMPY-00803 Fibronectin Protein, Human, Recombinant (aa 607-1265, His) Human HEK293
Fibronectin (FN) is a glycoprotein component of the extracellular matrix of the extracellular matrix (ECM) with roles in embryogenesis, development, and wound healing. More recently, FN has emerged as player in platelet ...
TMPY-04922 FAP Protein, Human, Recombinant (His), Biotinylated Human HEK293
Seprase, also known as 17 kDa melanoma membrane-bound gelatinase , Fibroblast activation protein alpha, Integral membrane serine protease and FAP, is a single-pass type II membrane protein which belongs to thepeptidase S...
TMPY-05636 G-CSF Protein, Mouse, Recombinant Mouse HEK293
Granulocyte-colony stimulating factor (G-CSF) is a growth factor and an essential cytokine belonging to the CSF family of hormone-like glycoproteins. It is produced by numerous cell types including immune and endothelial...
TMPY-04829 G-CSF Protein, Human, Recombinant Human HEK293
Granulocyte-colony stimulating factor (G-CSF) is a growth factor and an essential cytokine belonging to the CSF family of hormone-like glycoproteins. It is produced by numerous cell types including immune and endothelial...
TMPY-03945 Latent TGF beta 1 Protein, Rat, Recombinant (His) Rat HEK293
TGF-beta 1 is a member of the transforming growth factor beta (TGF-beta) family. The transforming growth factor-beta family of polypeptides are involved in the regulation of cellular processes, including cell division, d...
TMPY-04211 Latent TGF beta 1 Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293
TGF-beta 1 is a member of the transforming growth factor beta (TGF-beta) family. The transforming growth factor-beta family of polypeptides are involved in the regulation of cellular processes, including cell division, d...
TMPY-00608 TGF beta 1 Protein, Rat/Mouse, Recombinant Mouse,Rat HEK293
TGF-beta 1 is a member of the transforming growth factor beta (TGF-beta) family. The transforming growth factor-beta family of polypeptides are involved in the regulation of cellular processes, including cell division, d...
TMPY-01167 E-Selectin/CD62E Protein, Human, Recombinant (His) Human HEK293
E-selectin, also known as endothelial leukocyte adhesion molecule-1 (ELAM-1) and CD62E, is an inducible adhesion molecule that is expressed on the surfaces of stimulated vascular endothelial cells and is sometimes involv...
TMPH-02580 CHRAC1 Protein, Mouse, Recombinant (His & Myc) Mouse E. coli
Forms a complex with DNA polymerase epsilon subunit POLE3 and binds naked DNA, which is then incorporated into chromatin, aided by the nucleosome remodeling activity of ISWI/SNF2H and ACF1. Does not enhance nucleosome sl...
TMPH-02808 NPTX1 Protein, Mouse, Recombinant (His) Mouse E. coli
May be involved in mediating uptake of synaptic material during synapse remodeling or in mediating the synaptic clustering of AMPA glutamate receptors at a subset of excitatory synapses.
TMPH-02807 NPTXR Protein, Mouse, Recombinant (His & Myc) Mouse Baculovirus
May be involved in mediating uptake of synaptic material during synapse remodeling or in mediating the synaptic clustering of AMPA glutamate receptors at a subset of excitatory synapses.
TMPH-02159 SMARCC1 Protein, Human, Recombinant (His & SUMO) Human E. coli
Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Component of SWI/SNF chromatin remodeling complexes that carry out key enzymatic acti...
TMPJ-00447 MMP-3 Protein, Human, Recombinant (His) Human Human Cells
MMP3 is a member of the matrix metalloproteinase (MMP) family whose members are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, tissue rem...
TMPH-01879 PARP11 Protein, Human, Recombinant (His) Human E. coli
Mono-ADP-ribosyltransferase that mediates mono-ADP-ribosylation of target proteins. Plays a role in nuclear envelope stability and nuclear remodeling during spermiogenesis.
TMPY-05251 RbAp48 Protein, Mouse, Recombinant (His) Mouse Baculovirus-Insect Cells
Histone-binding protein RBBP4, also known as Retinoblastoma-binding protein 4, Retinoblastoma-binding protein p48, Chromatin assembly factor 1 subunit C, Chromatin assembly factor I p48 subunit, Nucleosome-remodeling fac...
TMPH-01228 DPYSL3 Protein, Human, Recombinant (His) Human E. coli
Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration.
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PARVA Protein, Human, Recombinant (His)
TMPJ-00242
Species: Human
Expression System: E. coli
CAPN1 Protein, Human, Recombinant (His)
TMPH-01029
Species: Human
Expression System: E. coli
FGF-16 Protein, Human, Cynomolgus, Recombinant
TMPY-00117
Species: Human,Cynomolgus
Expression System: Baculovirus-Insect Cells
CAPN2 Protein, Human, Recombinant (His)
TMPH-01031
Species: Human
Expression System: E. coli
RANK/TNFRSF11A Protein, Human, Recombinant (hFc)
TMPY-04142
Species: Human
Expression System: HEK293
Tetranectin Protein, Mouse, Recombinant (His)
TMPY-02785
Species: Mouse
Expression System: HEK293
SOST Protein, Human, Recombinant (His)
TMPY-00925
Species: Human
Expression System: HEK293
SOST Protein, Rat, Recombinant (His)
TMPY-01633
Species: Rat
Expression System: HEK293
MMP-9 Protein, Human, Recombinant (His)
TMPY-00888
Species: Human
Expression System: HEK293
MMP-9 Protein, Human, Recombinant
TMPY-01248
Species: Human
Expression System: HEK293
MMP-9 Protein, Mouse, Recombinant
TMPY-01919
Species: Mouse
Expression System: HEK293
FGF-2 Protein, Mouse, Recombinant (His)
TMPY-00210
Species: Mouse
Expression System: E. coli
MMP-12 Protein, Human, Recombinant (catalytic domain)
TMPY-02869
Species: Human
Expression System: E. coli
FGF-2 Protein, Human, Recombinant
TMPY-00749
Species: Human
Expression System: E. coli
TIE2 Protein, Human, Recombinant (His)
TMPY-01064
Species: Human
Expression System: HEK293
TIE2 Protein, Human, Recombinant (His & hFc)
TMPY-00930
Species: Human
Expression System: HEK293
EphB4 Protein, Mouse, Recombinant (hFc)
TMPY-01786
Species: Mouse
Expression System: HEK293
RANKL/TNFSF11/CD254 Protein, Human, Recombinant (E. coli)
TMPJ-00662
Species: Human
Expression System: E. coli
CTHRC1 Protein, Human, Recombinant (His)
TMPY-01395
Species: Human
Expression System: HEK293
MMP-8 Protein, Human, Recombinant
TMPY-01884
Species: Human
Expression System: HEK293
Osteoactivin/GPNMB Protein, Mouse, Recombinant (His)
TMPY-03014
Species: Mouse
Expression System: HEK293
HSP90 alpha Protein, Human, Recombinant
TMPY-01478
Species: Human
Expression System: E. coli
PDGFC Protein, Mouse, Recombinant (His)
TMPY-04976
Species: Mouse
Expression System: Yeast
Progranulin Protein, Human, Recombinant (His)
TMPY-00978
Species: Human
Expression System: HEK293
RANKL/TNFSF11/CD254 Protein, Human, Recombinant (mFc)
TMPY-03674
Species: Human
Expression System: HEK293
RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (hFc)
TMPY-02726
Species: Mouse
Expression System: HEK293
FAP Protein, Human, Recombinant (His)
TMPY-02154
Species: Human
Expression System: HEK293
RANKL/TNFSF11/CD254 Protein, Human, Recombinant
TMPY-03364
Species: Human
Expression System: HEK293
TGF beta 1 Protein, Human/Rhesus/Cynomolgus/Canine, Recombinant
TMPY-02638
Species: Human,Rhesus,Cynomolgus,Canine
Expression System: CHO
HMGB1 Protein, Mouse, Recombinant (hFc)
TMPY-02590
Species: Mouse
Expression System: HEK293
Latent TGF beta 1 Protein, Human, Recombinant (His)
TMPY-01133
Species: Human
Expression System: HEK293
Latent TGF beta 1 Protein, Mouse, Recombinant (His)
TMPY-00500
Species: Mouse
Expression System: HEK293
HMGB1 Protein, Human, Recombinant (aa 1-215, His)
TMPY-01848
Species: Human
Expression System: HEK293
FAP Protein, Cynomolgus, Recombinant (His)
TMPY-04962
Species: Cynomolgus
Expression System: HEK293
Fibronectin Protein, Human, Recombinant (aa 607-1265, His)
TMPY-00803
Species: Human
Expression System: HEK293
FAP Protein, Human, Recombinant (His), Biotinylated
TMPY-04922
Species: Human
Expression System: HEK293
G-CSF Protein, Mouse, Recombinant
TMPY-05636
Species: Mouse
Expression System: HEK293
G-CSF Protein, Human, Recombinant
TMPY-04829
Species: Human
Expression System: HEK293
Latent TGF beta 1 Protein, Rat, Recombinant (His)
TMPY-03945
Species: Rat
Expression System: HEK293
Latent TGF beta 1 Protein, Cynomolgus, Recombinant (His)
TMPY-04211
Species: Cynomolgus
Expression System: HEK293
TGF beta 1 Protein, Rat/Mouse, Recombinant
TMPY-00608
Species: Mouse,Rat
Expression System: HEK293
E-Selectin/CD62E Protein, Human, Recombinant (His)
TMPY-01167
Species: Human
Expression System: HEK293
CHRAC1 Protein, Mouse, Recombinant (His & Myc)
TMPH-02580
Species: Mouse
Expression System: E. coli
NPTX1 Protein, Mouse, Recombinant (His)
TMPH-02808
Species: Mouse
Expression System: E. coli
NPTXR Protein, Mouse, Recombinant (His & Myc)
TMPH-02807
Species: Mouse
Expression System: Baculovirus
SMARCC1 Protein, Human, Recombinant (His & SUMO)
TMPH-02159
Species: Human
Expression System: E. coli
MMP-3 Protein, Human, Recombinant (His)
TMPJ-00447
Species: Human
Expression System: Human Cells
PARP11 Protein, Human, Recombinant (His)
TMPH-01879
Species: Human
Expression System: E. coli
RbAp48 Protein, Mouse, Recombinant (His)
TMPY-05251
Species: Mouse
Expression System: Baculovirus-Insect Cells
DPYSL3 Protein, Human, Recombinant (His)
TMPH-01228
Species: Human
Expression System: E. coli
--------- More ---------
Cat No. Product Name
L8300 Chromatin Modification Compound Library

256 compounds
A unique collection of 256 compounds targeting chromatin remodeling pathway for high throughput screening (HTS) and high content screening (HCS);
L9810 Anti-Fibrosis Compound Library

1180 compounds
A unique collection of 1180 potential anti-fibrosis compounds, can be used in HTS and HCS;

Libraries

Chromatin Modification Compound Library
L8300
Compounds: 256
Anti-Fibrosis Compound Library
L9810
Compounds: 1180
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