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pt 523

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  • Inhibitors & Agonists
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    TargetMol | Inhibitors_Agonists
Talotrexin
PT523
T73085113857-87-7
Talotrexin (PT523), an analog of Aminopterin, is a nonpolyglutamatable classic antifolate that specifically inhibits the reduced folate carrier (RFC), selectively impeding RFC transport and targeting dihydrofolate reductase (DHFR) to demonstrate antitumor activity and inhibit tumor growth [1] [2].
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1-2 weeks
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