probes

2-Di-1-ASP is a mono-stryryl dye and widely used as mitochondrial stain and groove-binding fluorescent probes for double-stranded DNA. It has selective for G-quadruplex (G4) and double-stranded DNA.

Fluorescein Sodium (VST-1001) is a phthalic indicator dye. It is used therapeutically as a diagnostic aid in corneal injuries and corneal trauma.

EDANS sodium (5-(2-Aminoethylamino)-1-naphthalenesulfonic acid sodium salt) is a donor for developing FRET-based nucleic acid probes that is widely used in real time PCR assays.

TMB dihydrochloride (Sure Blue TMB dihydrochloride) is an enzyme-linked immunosorbent assays (ELISA) and an excellent colorimetric substrate for the detection of horseradish peroxidase (HRP)-labeled probes used in staining procedures immunohistochemistry.

TMB (BM blue) is a chromogenic substrate used in staining procedures in immunohistochemistry and as a visualizing reagent in ELISA.

3-Cyano-7-hydroxycoumarin (3-Cyanoumbelliferone) is a macrophage inhibitor of macrophage inhibitory factor (MIF) interconjugate isomerase with a Ki of 2.9 μM. 3-Cyano-7-hydroxycoumarin belongs to the group of coumarin derivatives, which can be used as molecular probes and fluorescent dyes.

Dabcyl acid, SE (Dabcyl, SE) is the amino-reactive form of Dabcyl acid and used to prepare a variety of FRET-based probes that contain Dabcyl acid.

5(6)-FITC (Fluorescein isothiocyanate), or Fluorescein 5(6)-isothiocyanate, is a versatile amine-reactive derivative of fluorescein dye. It serves as an effective label for antibodies and other probes, finding utility in fluorescence microscopy, flow cytometry, and immunofluorescence-based assays such as ELISA and Western blotting.

Sulfo-Cy3 NHS ester TEA (146368-16-3 free base) is a sulfonated cyanine-based fluorescent labeling reagent with an excitation wavelength of approximately 550 nm and an emission wavelength of approximately 570 nm. Sulfo-Cy3 NHS ester TEA can be used as an amine-reactive fluorescent probe for labeling biomolecules such as antibodies, proteins, peptides, and nucleic acid probes. Sulfo-Cy3 NHS ester TEA is also suitable for applications including immunofluorescence staining, in situ hybridization, and flow cytometry analysis.

(±)-ANAP is the amino acid analog of prodan. It can be used as a fluorescent probes and enhance environmental sensitivity.

(±)-ANAP hydrochloride is the amino acid analog of prodan. It can be used as a fluorescent probes and enhance environmental sensitivity.

Acridinium C2 NHS ester is a chemiluminescent label known for its reactivity, making it suitable for developing protein and nucleic acid probes. This compound is widely used in bioanalytical and diagnostic applications, offering high-sensitivity detection solutions. It is particularly valuable in medical research for monitoring and analyzing biomolecules.

5-Aminofluorescein hydrochloride (5-AF hydrochloride) is a protein fluorescence labeling reagent known for its outstanding fluorescent properties and is extensively utilized in biomedical research for cell imaging and molecular probes. This compound enables the observation of protein localization and dynamic changes, providing insightful biological understanding. Additionally, 5-Aminofluorescein hydrochloride is employed to detect interactions between biomolecules, aiding in the elucidation of complex biological processes.

WYneC is a chemically selective probe utilized for the detection of thiolated proteins in live cells. This probe is selective for dipeptides that contain thio-amino acids and can be further coupled with azide-containing fluorescent probes for detection purposes.

WYneN is a chemoselective probe designed for the detection of sulfenylated proteins in living cells. In these cells, WYneN binds to sulfenylated proteins and can further interact with azide-containing fluorescent probes for detection purposes.

Fmoc-protected fluorescent amino acid is designed for solid-phase peptide synthesis, specifically for crafting PAINT imaging probes. It features excitation and emission maxima (λ) at 488 nm and 601 nm, respectively.

Sulfo-QSY21-NHS is a fluorescent dye featuring an NHS group that can react with amine groups (-NH2) in proteins or other molecules to form stable amide bonds. It is suitable for synthesizing active group probes.

Pyrromethene 567 is a fluorescent dye (Ex/Em ≈ 518/547 nm) that is commonly used for labeling biomolecules such as proteins, nucleotides, and oligonucleotides. It can also be used to prepare various fluorescent probes or labels, including lipid molecules and microspheres, and is widely applied in bioimaging and molecular detection studies.

Cyanine3 carboxylic acid is a non-toxic red fluorescent dye that serves as a non-reactive fluorophore for experimental controls and calibration. It can also be conjugated with targeting active molecules to create fluorescent probes for rapid detection of molecular reactions. [Ex/Em(nm)=550/570nm]

Cyamine3.5 NHS ester is a squaraine dye utilized in the development of fluorescent probes and biological labeling, characterized by its intermediate wavelength fluorescence emission properties. Specially designed for reactions with amino groups to form stable covalent bonds, it is ideal for labeling biomolecules. Ex/Em(nm)=591/604.

DMT-BH2 amidite (BHQ-2 DMT amidite) is a black quencher dye used in the synthesis of qPCR dual-labeled oligonucleotide probes with 5'-quenchers. This quencher is ideal for HEX, JOE, ROX, Cyanine5, and other dyes that emit in the spectral orange and red regions.

BP Fluor 405 alkyne triTEA is a blue fluorescent dye frequently used in multicolor applications, such as flow cytometry and super-resolution microscopy employing STORM. It is optimally excited by the 407 nm spectral line of a krypton laser or a 408 nm violet laser diode. BP Fluor 405 alkyne triTEA reacts with azides via a copper-catalyzed click reaction (CuAAC) to form stable triazole linkages. For applications sensitive to the presence of copper, copper-free detection probes (BP Fluor 405 DBCO) are also available.

DMT-BH1 amidite (BHQ-1 DMT amidite) is an effective dark quencher with a broad absorption spectrum that encompasses the visible range, peaking in the green to yellow area. It is employed in the synthesis of qPCR dual-labeled oligonucleotide probes with a 5'-quencher DusQ 1 and in other FRET applications for multiplex analysis.

NBD-hydrazine serves as a fluorescent probe that reacts with aldehydes and ketones, exhibiting excitation and emission maxima at 468 and 535 nm, respectively. Additionally, it is utilized as a precursor in creating malondialdehyde-reactive fluorescent probes and as a synthetic intermediate for developing cupric and chromic ion colorimetric sensors.