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Results for "

probe

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    443
    TargetMol | Inhibitors_Agonists
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    TargetMol | Inhibitory_Antibodies
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    TargetMol | Inhibitors_Agonists
LP99
T157841808951-93-0
LP99 is an epigenetic probe. LP99 disrupts the binding of BRD7 and BRD9 to chromatin in cells. LP99 is an effective and selective inhibitor of the BRD7 and BRD9 bromodomains (Kd: 99 nM against BRD9).
  • $36
In Stock
Size
QTY
TargetMol | Inhibitor Sale
Copper probe CF4
Copper probe CF-4, Copper probe CF 4, Copper fluor CF4, CF4 prob
T310082365532-64-3In house
Copper probe CF4 (Copper fluor CF4) is a fluorescent copper probe that can be used to study colon cancer.
  • $165 TargetMol
In Stock
Size
QTY
Cysteine thiol probe
Methyl (4-bromobenzoyl)-L-cysteinate
T84831947408-74-3
Cysteine thiol probe (Methyl (4-bromobenzoyl)-L-cysteinate) is a chemoselective thiol probe for detection of electrophilic metabolites
  • $43
In Stock
Size
QTY
TargetMol | Inhibitor Sale
Protein kinase affinity probe 1
T125622098621-90-8
Protein kinase affinity probe 1 is used for the functional identification of protein kinases (PKs).
  • Inquiry Price
3-6 months
Size
QTY
Hras-1Y i-motif Probe-1
T32104
Hras-1Y i-motif Probe-1 is a probe of the hras-1Y i-motif which selectively and directly interacts with it.
  • Inquiry Price
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QTY
Aldehyde Reactive Probe TFA
ARP TFA
T35575627090-10-2
Aldehyde Reactive Probe TFA (ARP TFA) is an aldehyde-reactive probe used to detect the level of abasic sites in plant mRNA.
  • $198
35 days
Size
QTY
Difluorinated H2S Fluorescent Probe 1
T377202103919-91-9
Difluorinated H2S probe 1 is a fluorescent probe for hydrogen sulfide (H2S).1It selectively fluoresces in the presence of H2S over Zn2+, Fe3+, S2O32-, ClO-, SO32-, H2O2, NO2-, cysteine (Cys), homocysteine (Hcy), and glutathione (GSH) when used at a concentration of 1 μM. Difluorinated H2S probe 1 displays excitation/emission maxima of 365/450 nm, respectively. 1.Zhang, J., Gao, Y., Kang, X., et al.o,o-Difluorination of aromatic azide yields a fast-response fluorescent probe for H2S detection and for improved bioorthogonal reactionsOrg. Biomol. Chem.15(19)4212-4217(2017)
  • TBD
35 days
Size
QTY
Melanin probe-1
T388551420844-62-7
Melanin probe-1, an 18F-picolinamide-based PET probe, is utilized for PET imaging of malignant melanoma. It demonstrates remarkable tumor targeting efficacy, superior tumor imaging contrasts, favorable biodistribution profiles, and robust in vivo stability.
  • $68
5 days
Size
QTY
Kbz probe 1
T402352606820-58-8
Kbz probe 1, an adaptable probe utilized for examining histone benzoylation and interactions within living cells, showcases extensive versatility.
  • $1,520
Backorder
Size
QTY
CXCR4 probe 1
T643062077985-50-1
CXCR4 probe 1 (compound 5) is a potent and specific CXCR4-targeted PET tracer that acts on the CXCR4-specific antagonist TN14003 (IC50: 6.9 nM). It has potential as a CXCR4-specific imaging probe for the diagnosis and prognostic monitoring of inflammatory diseases, CXCR4-positive tumors, and metastatic tumors.
  • $1,520
10-14 weeks
Size
QTY
Melanin probe-2
T64640
Melanoma is a lethal skin cancer. The early detection of melanoma using positron emission tomography (PET) probes is critical for improving the survival of melanoma patients. Melanin probe-2 is a non-radioactive bromo-picolinamide precursor that has been used for the synthesis of18F-picolinamides based PET probe (melanin probe-1). The tumor-targeting efficacy and imaging property of three melanin probes were evaluated in B16F10 tumor-bearing mice.18F-1 and18F-3 had much lower tumor uptake compared with18F-2 (Melanin probe-2), which were 12.74 ± 1.70, 16.61 ± 2.60, and 16.87 ± 1.23 %ID g at 0.5, 1, and 2 h, respectively[1].
    7-10 days
    Inquiry
    Cyclopropenone probe 1
    T72328
    Cyclopropenone probe 1 can specifically and efficiently modify a triple-negative breast cancer driver, glutathione S-transferase pi-1 (GSTP1) , by covalently binding at the catalytic active site.
    • $1,520
    6-8 weeks
    Size
    QTY
    BLT2 probe 1
    T742122893803-05-7
    BLT2 Probe 1 (Compound 13), a fluorescent probe derived from the synthetic BLT2 agonist CAY10583, offers a robust tool for exploring BLT2 receptor ligand pharmacology across various assay systems [1]. As BLT2 is a valuable target for treatments in diabetic wound healing and gastrointestinal lesions, this probe facilitates relevant biomedical research.
    • Inquiry Price
    8-10 weeks
    Size
    QTY
    Y1R probe-1
    T744592773476-41-6
    Compound 39, also known as Y1R probe-1, is a high-affinity fluorescent probe targeting the Neuropeptide Y Y1 Receptor, with potential applications in cancer research [1].
    • Inquiry Price
    8-10 weeks
    Size
    QTY
    cb2r probe 1
    T746042634714-79-5
    CB2R Probe 1, a cannabinoid 2 receptor (CB2R) fluorescent probe, exhibits both safety and environmental friendliness, boasting a dissociation constant (K i) of 130 nM. Notably, it demonstrates low cytotoxicity within cancer cells [1].
    • Inquiry Price
    Size
    QTY
    G-quadruplex DNA fluorescence probe 1
    T74613
    Compound E1, also known as G-quadruplex DNA fluorescence probe 1, is a selective fluorescent probe targeting G-quadruplex DNA. It possesses the ability to penetrate membranes and enter living cells, demonstrating low cytotoxicity [1].
    • Inquiry Price
    Size
    QTY
    PARP7-probe-1
    T753462379390-76-6
    PARP7-probe-1, a chemiluminescent-labeled and biotinylated probe, selectively binds to the PARP7 active site, facilitating research into PARP7 function [1].
    • $2,230
    8-10 weeks
    Size
    QTY
    H2S probe 1
    T89070
    H2S probe 1 (compound 1NND), a derivative of nitrobenzofurazan (NBD), exhibits antitumor activity. It demonstrates cytotoxicity towards human pancreatic cancer cells, MIA PaCa-2, with an IC50 value of 77.9 nM, and shows high affinity for the human telomeric G-quadruplex with a Kd of 1.72 μM. H2S probe 1 is utilized for cancer research.
    • Inquiry Price
    Size
    QTY
    Probenecid
    Benemid
    T045757-66-9
    Probenecid (Benemid) is a benzoic acid derivative with antihyperuricemic property.
    • $37
    In Stock
    Size
    QTY
    Eprobemide
    LIS 630
    T505387940-60-1
    Eprobemide (LIS 630) is a non-competitive reversible inhibitor of monoamine oxidase A (MAO-A).
    • $34
    In Stock
    Size
    QTY
    TargetMol | Inhibitor Sale
    Probenecid sodium
    T20413623795-03-1
    Probenecid sodium is the sodium salt of Probenecid, a potent and selective agonist of transient receptor potential vanilloid 2 (TRPV2) channels. Additionally, Probenecid acts as an inhibitor of pannexin 1 channels.
    • Inquiry Price
    10-14 weeks
    Size
    QTY
    Iprobenfos
    Ricid P, Ricid II, Kitazin P, Kitazin L
    T2553926087-47-8
    Iprobenfos (IBP) is used as an organophosphorus pesticide.
    • $1,520
    Backorder
    Size
    QTY
    Probestin
    T25987123652-87-9
    Probestin is an aminopeptidase M inhibitor, isolated from Streptomyces azureus MH663-2F6.
    • $1,520
    Backorder
    Size
    QTY
    Exiproben
    DCH 21
    T3173626281-69-6
    Exiproben is a biochemical.
    • $1,520
    Backorder
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    QTY