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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T1009 | Estrone | Oestrone,Fluoroethyl,Aquacrine | Estrogen Receptor/ERR , Estrogen/progestogen Receptor , Endogenous Metabolite |
Estrone (Aquacrine) is an aromatized C18 steroid with a 3-hydroxyl group and a 17-ketone, a major mammalian estrogen. It is converted from ANDROSTENEDIONE directly, or from TESTOSTERONE via ESTRADIOL. In humans, it is pr... | |||
T29164 | WY-47766 | WY47766 | |
WY-47766, a proton pump inhibitor, is used potentially for the treatment of postmenopausal osteoporosis. | |||
TQ0172 | 2''-O-Rhamnosylicariside II | Others | |
2''-O-Rhamnosylicariside II might be beneficial for improving postmenopausal osteoporosis. It shows potent antioxidant activity, with IC50 values of 11.5 ug/mL and 90.5 uM. | |||
T1216 | Diethylstilbestrol | Stilbestrol,DES | Estrogen Receptor/ERR , Estrogen/progestogen Receptor |
Diethylstilbestrol (DES) is used in the treatment of menopausal and postmenopausal disorders. | |||
TJS0856 | Dalbergin | 6-Hydroxy-7-Methoxy-4-Phenylcoumarin | Others |
1. Dalbergin (6-Hydroxy-7-Methoxy-4-Phenylcoumarin) exhibits similar bone conserving effect against bone-loss as estradiol treatment, it as a therapeutic candidate against postmenopausal osteoporosis. 2. Dalbergin preven... | |||
T1549 | Raloxifene hydrochloride | LY156758 hydrochloride,Raloxifene HCl,LY139481 hydrochloride,Keoxifene hydrochloride,LY156758 (Keoxifene) HCl | Estrogen Receptor/ERR , Others , MAO , Estrogen/progestogen Receptor , Autophagy |
Raloxifene hydrochloride (LY156758 hydrochloride) is a second generation selective estrogen receptor modulator (SERM) used to prevent osteoporosis in postmenopausal women. It has estrogen agonist effects on bone and chol... | |||
T6399 | AZD1981 | GPR , Prostaglandin Receptor | |
AZD1981 is an effective and specific CRTh2 (DP2) receptor antagonist (IC50: 4 nM), showing >1000-fold selectivity over more than 340 other enzymes and receptors, including DP1. AZD1981 has been used in trials studying th... | |||
T6739 | Zoledronic Acid | CGP-4244,CGP42446A,Zoledronate,CGP 42446,ZOL 446,Zometa | Apoptosis , Rho , Autophagy |
Zoledronic Acid (ZOL 446) is a bisphosphonate. Zoledronic Acid (ZOL 446) is used to prevent skeletal fractures in patients with cancers such as multiple myeloma and prostate cancer. It can also be used to treat hypercalc... | |||
T28870 | Strontium Malonate | NBS-101,NBS 101,NBS101 | |
Strontium Malonate, a calcium-sensing receptor agonist, is used potentially for the treatment of postmenopausal osteoporosis. | |||
TP1028 | Calcitonin, eel | Thyrocalcitonin eel | |
Calcitonin, eel is a peptide hormone that plays a crucial role in maintaining calcium balance within the body. It is extensively utilized in the scientific investigation of postmenopausal osteoporosis, a condition charac... | |||
TP1027 | Calcitonin, eel TFA (57014-02-5 free base) | Thyrocalcitonin eel (TFA),Calcitonin, eel TFA | |
Calcitonin,eel TFA is a thyroid hormone polypeptide that can regulate calcium homeostasis and is widely used in the study of postmenopausal osteoporosis. | |||
T78372 | Calcitonin, eel TFA | Thyrocalcitonin eel TFA | |
Calcitonin (eel TFA) is a thyroid hormone peptide that plays a role in regulating calcium homeostasis and is commonly utilized in the study of postmenopausal osteoporosis [1]. | |||
T77769 | Menotropin | Human Menopausal Gonadotrophin | |
Menotropin (Human Menopausal Gonadotropin) is a hormonally active drug for the treatment of fertility disorders, extracted from the urine of postmenopausal women. | |||
TN4334 | Isotaxiresinol | TNF | |
Isotaxiresinol prevents d-GalN/LPS-induced hepatic injury by inhibiting hepatocyte apoptosis through the blocking of TNF-alpha and IFN-gamma production by activated macrophages and direct inhibition of the apoptosis indu... | |||
T36913 | 17-Epiestriol | ||
17-Epiestriol is a metabolite of estrone .1It is formed from estroneviaa 16α-hydroxy estrone intermediate by reduction of the C-17 ketone. 17-Epiestriol binds to estrogen receptor α (ERα) and ERβ with relative binding af... |