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(2)
By Target- Apoptosis
- Akt(1)
- Autophagy(1)
- JNK(1)
- PDK(1)
- mTOR(1)
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Results for "
polyphyllin i
" in TargetMol Product Catalog- Inhibitors & Agonists2
- Natural Products2
Polyphyllin I 
T389550773-41-6
Polyphyllin D induces apoptosis via the mitochondrial apoptotic pathway as evidenced by decreased Bcl-2 expression levels, disruption of MMP and increased Bax, cytochrome C, and cleaved-caspase-3 levels. Polyphyllin D has an anti-angiogenic effect. Polyphyllin D has toxicity in human RBCs as well as its underlying mechanism for the hemolysis and eryptosis erythroptosis. Polyphyllin D has strong anticancer activity, can overcome drug resistance in R-HepG2 cells and elicit programmed cell death via mitochondrial dysfunction.
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Polyphyllin II
Chonglou Saponin II
T389476296-72-5
Polyphyllin II (Chonglou Saponin II) has hemostasis, expectorant, bacteriostasis, anticytotoxic, anti-pregnancy kill sperm effects.
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