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polθ-in-6

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  • Inhibitors & Agonists
    2
    TargetMol | Inhibitors_Agonists
Polθ-IN-6
T2009183058496-94-6
Polθ-IN-6 (Compound 89) is an inhibitor of DNA polymerase theta (Polθ) and exhibits antitumor activity.
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3-6 months
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AB25583
T2001012565637-94-5
AB25583 is a small molecule inhibitor of Polθ helicase (Polθ-hel) with an IC50 of 6 nM. It selectively kills cells deficient in BRCA1 2 and synergizes with Olaparib in cancer cells harboring pathogenic BRCA1 2 mutations. AB25583 can be utilized in tumor research.
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4-6 weeks
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