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phenylethanolamine-n-methyltransferase (pnmt)

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  • Inhibitors & Agonists
    3
    TargetMol | Inhibitors_Agonists
LY 78335
1-(2,3-Dichlorophenyl)ethanamine hydrochloride
T2295639959-66-5
LY 78335 (1-(2,3-Dichlorophenyl)ethanamine hydrochloride) is a phenylethanolamine-N-methyltransferase (PNMT) inhibitor.
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LY 134046
LY-134046,LY134046,Lilly 134046
T2787271274-97-0
LY 134046 is an inhibitor of phenylethanolamine-N-methyltransferase (PNMT).
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8-10 weeks
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PNMT-IN-1
T81432
PNMT-IN-1 (inhibitor 4) is a selective second generation inhibitor [1] of phenylethanolamine N-methyltransferase (PNMT), exhibiting a Ki value of 1.2 nM and an IC50 value of 81 nM. Additionally, it disrupts the activity of DNMT1 and DNMT3b, with IC50 values of 61 μM and 17 μM, respectively, and antagonizes the action of epinephrine.
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