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phenylbiguanide

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  • Inhibitors & Agonists
    3
    TargetMol | Inhibitors_Agonists
Phenylbiguanide
PBG, N-Phenylbiguanide, 1-Phenylbiguanide
T7135102-02-3
Phenylbiguanide (N-Phenylbiguanide) is a 5-HT3 receptor selective agonist(EC50 : 3.0±0.1 μM)
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1-phenylbiguanide hcl
Phenylbiguanide hydrochloride
PDK026955-57-2
Compound PDK0269, as 5-HT3 receptor agonists(3–100 μM, pEC50 5.05±0.06), acutely increased XII (hypoglossal) burst frequency and regularity, and decreased bursts episode . Phenylbiguanide produced a dose-related (10-500 microM) increase in the release of dopamine (280-2000%). When nomifensine (5 microM) was included in the Ringer solution, the effect of Compound PDK0269 on the release of dopamine was ameliorated or inhibited.
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7-10 days
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