officinale

Guaifenesin (Guaiphenesin) is an expectorant that also has some muscle relaxing action. It is used in many cough preparations.

Zingerone (Vanillylacetone) is a nontoxic methoxyphenol isolated from Zingiber officinale, with potent anti-inflammatory, antidiabetic, antidiarrhoeic, antilipolytic, antispasmodic, and anti-tumor properties. Zingerone (Gingerone) alleviates oxidative stress and inflammation, down-regulates NF-κB mediated signaling pathways, acts as an anti-mitotic agent, and inhibits the growth of neuroblastoma cells.

Gordonoside J, a compound isolated from the stem of Chrysanthemum officinale, inhibits LPS-induced nitric oxide production in rat polymorphonuclear leukocytes (PMNS).

Gordonoside I, a compound isolated from the stem of Chrysanthemum officinale, strongly inhibited the production of nitric oxide in LPS-activated macrophages with an IC50 value of 0.14 μM.

(Z)-Ligustilide (Ligustilide A) , an active ingredient isolated from the medicinal plants Angelica acutiloba and Cnidium officinale, inhibits benzo(a)pyrene-induced CYP1A1 upregulation in cultured human keratinocytes via ROS-dependent Nrf2 activation.

Isoviolanthin reduces the migratory and invasive capacities of TGF-β1-treated HCC cells without cytotoxic effects on normal live cells and has potential as a therapeutic agent for the treatment of advanced-stage metastatic HCC. Isoviolanthin is a flavonoid glycoside extracted from the leaves of Dendrobium Officinale.

Rhein (NSC 38629) is an anthraquinone compound extracted from Polygonaceae Rheum Officinale with anti-inflammation and antitumor activities.

Taraxasterol (Taraxasterin) is compound with anti-inflammatory activity.

(-)-Rabdosiin, identified as a novel phenolic marker in Symphytum officinale L., exhibits antioxidant, neuroprotective, and anti-HIV activities [1].

Neonuezhenide is a phenolic compound isolated from Ligustrum officinale, which has strong antioxidant effects on free radical-induced hemolysis of red blood cells.

(–)-β-Sesquiphellandrene, a sesquiterpene identified in Z. officinale, exhibits antiviral and anticancer properties. It effectively inhibits rhinovirus IB virus replication in a plaque reduction assay with an IC50 of 0.44 µM. Additionally, at a concentration of 10 µM, it demonstrates cytotoxicity to HCT116 cells.

8-Gingerdione can be isolated from Ginger (Zingiber officinale). It does not significantly inhibit the production of the inflammatory mediators NO, TNF-α, and IL-6.