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By Target- Apoptosis
- COX(1)
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Results for "
nitroaspirin
" in TargetMol Product Catalog- Inhibitors & Agonists1
Nitroaspirin
NCX 4016
T16328175033-36-0
Nitroaspirin (NCX 4016) is a nitric oxide donor and a nitro-derivative of Aspirin that inhibits cyclooxygenase. It induces cell cycle arrest and apoptosis in Cisplatin-resistant human ovarian cancer cells by down-regulating EGFR PI3K STAT3 signaling and modulating Bcl-2 family proteins. Additionally, Nitroaspirin possesses antithrombotic and antiplatelet properties and acts as a direct and irreversible inhibitor of COX-1.
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