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nav1.6 channel

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    8
    TargetMol | All_Pathways
  • Compound Libraries
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    TargetMol | Compound_Libraries
  • Peptide Products
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    TargetMol | Recombinant_Protein
GrTx1
T80179
GrTx1, a peptide toxin derived from Grammostola rosea spider venom, selectively inhibits sodium channels Nav1.1, Nav1.2, Nav1.3, Nav1.4, Nav1.6, and Nav1.7, with IC50 values of 0.63 µM, 0.23 µM, 0.77 µM, 1.29 µM, 0.63 µM, and 0.37 µM, respectively [2]. This compound has applications in neurological disease research [1].
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OD1
TP1972
Potent rat Nav1.7, human Nav1.4 and rat Nav1.6 channel activator (EC50 values are 7, 10 and 47 nM, respectively). Exhibits minimal activation at mammalian Nav1.2, Nav1.3 and Nav1.5 (EC50 values >3 μM). Inhibits fast inactivation on all channels. Increases
  • $1,327
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Poneratoxin acetate
TP3045
Poneratoxin acetate is a neurotoxic peptide and modulator of NaV1.6/NaV1.7, lowering the activation threshold of voltage-gated sodium channels and causing pain.
  • $49
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