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Results for "
mucormycosis
" in TargetMol Product Catalog- Inhibitors & Agonists3
- Peptide Products2
Isavuconazonium sulfate
Cited
T3934946075-13-4
Isavuconazonium sulfate is hydrolyzed by plasma esterases to yield the active moiety isavuconazole. Isavuconazole binds to and inhibits the fungal cytochrome P450 family enzyme lanosterol 14-alpha-demethylase (CYP51), which catalyzes the demethylation of
- $68
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QTY
CitedMGQTNDGAYRDPTDNN sodium
MGQTNDGAYRDPTDNN from CotH3 sodium
TP2517
MGQTNDGAYRDPTDNN sodium is an antigenic and surface-exposed peptide from CotH3. CotH3 mediates fungal invasion of host cells during mucormycosis.
- $195
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CotH3 peptide
TP3806
The CotH3 peptide is a functional peptide unique to mucormyetes that can bind to the host GRP78 receptor, facilitating entry into endothelial cells. Monoclonal antibodies produced against the CotH3 peptide can protect immunocompromised mice from mucormycosis caused by Rhizopus delemar (R. delemar) and other mucormyetes. Additionally, the CotH3 peptide works synergistically with antifungal drugs to protect diabetic ketoacidosis (DKA) mice from R. delemar infections.
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