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msi-1436

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  • Inhibitors & Agonists
    4
    TargetMol | Inhibitors_Agonists
MSI-1436
Aminosterol-1436,Trodusquemine
T12116186139-09-3
MSI-1436 is a selective, non-competitive inhibitor of the enzyme protein-tyrosine phosphatase 1B (PTB1B) with an IC50 of approximately 1 μM.
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8-10 weeks
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MSI-1436 lactate
Trodusquemine lactate,Aminosterol-1436 lactate
T121171309370-86-2
MSI-1436 lactate is a selective, non-competitive inhibitor of the enzyme protein-tyrosine phosphatase 1B (PTP1B) with an IC50 of approximately 1 μM.
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MSI-1701
T12116L390808-64-7
MSI-1701, an analogue of MSI-1436, enhances (MSI-1436) activity by increasing (pMEK) and (pERK) phosphorylation, thus promoting (PI3K AKT) pathway signaling and inhibiting apoptosis in neuronal cells, which may contribute to its neuroprotective effects.
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3-6 months
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DPM-1001 trihydrochloride
T72216
DPM-1001 trihydrochloride, an analog of the specific protein-tyrosine phosphatase (PTP1B) inhibitor MSI-1436, is a potent, specific, non-competitive, orally active inhibitor of PTP1B with an IC50 of 100 nM, exhibiting anti-diabetic properties.
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8-10 weeks
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