mogroside iii

Mogroside III, a triterpenoid glycoside and nonsugar sweetener, is transformed by human intestinal bacteria to release secondary glycoside (mogroside IIA1) and aglycone [mogrol].

Mogroside III-A1 is a triterpenoid glycoside derived from Siraitia grosvenorii Swingle, serving as a nonsugar sweetener.

Mogroside III-A2 exhibits inhibitory effects with IC50 values of 346-400 mol ratio/32 pmol TPA. and shows weak inhibitory effects on activation of (+/-)-(E)-methyl-2-[(E)-hydroxyimino]-5-nitro-6-methoxy-3-hexemide (NOR 1), a nitric oxide (NO) donor.

Mogroside III-E, a cucurbitane-type compound isolated from Siraitia grosvenorii, exhibits anti-inflammatory activity by attenuating LPS-induced acute lung injury in mice through the regulation of the TLR4/MAPK/NF-κB axis via AMPK activation. Additionally, it demonstrates anti-fibrotic activity by reducing pulmonary fibrosis through Toll-Like receptor 4 pathways.

11-Deoxymogroside IIIE is a natural product isolated from Siraitia grosvenorii, suitable for biochemical experiments and drug synthesis research.

11-Dehydroxymogroside III is a useful organic compound for research related to life sciences. The catalog number is T123897 and the CAS number is 942612-68-2.

11-Oxomogroside III is a natural product from Siraitia grosvenorii Swingle.

11-Oxomogroside IIIE is a cucurbitane triterpene glycoside isolated from Siraitia grosvenorii (Lo Han Kuo), a traditional Chinese fruit used as a pulmonary demulcent for conditions including dry cough, sore throat, thirst, and constipation. Triterpenoids from this plant were evaluated for inhibition of Epstein–Barr virus early antigen induction by TPA in Raji cells, a primary screen for antitumor promoters, amongst all tested compounds, 11-Oxomogroside IIIE exhibited strong suppression with 70–100% inhibition at 1 × 10³ mol ratio/TPA.

11-O-Mogroside IIIA1 is a natural product that can be used in related research in the field of life sciences. Its product number is TN8824.

Lo Han Kuo extract is a high intensive sweetening agent with desirable health benefits, such as prevention of dental caries through specific antibacterial properties, no-calorie levels related to obesity, and a low glycemic index to help manage blood suga