moa

Proxalutamide is a potent antagonist of the androgen receptor (AR).

MOA-stilbene, also known as 3-Methoxy-2-(2-styrylphenyl)propenic acid methyl ester, is a fluorescence inhibitor. MOA-stilbene is a new tool for investigation of the reactions of the chloroplast cytochrome bf complex. MOA-stilbene is known to be a specific inhibitor of the Qo site of mammalian cytochrome bc 1 complex.

Compound 12d is a potent ALK5 inhibitor with an IC50 of 7nM.

Hydroxyzine Pamoate (Bobsule) is a histamine H1 receptor antagonist that is effective in the treatment of chronic urticaria, dermatitis, and histamine-mediated pruritus. Unlike its major metabolite CETIRIZINE, it does cause drowsiness. It is also effective as an antiemetic, for relief of anxiety and tension, and as a sedative.

Oxantel Pamoate (Oxantel embonate) is used as an Antinematodal agent.

Pyrantel pamoate (Pyrantel embonate) is a depolarizing neuromuscular blocking agent. This compound is commonly used as an anthelmintic to treat parasitic worm infections, effectively paralyzing nematodes by inhibiting their neuromuscular activity.

2-Bromoacetamide (α-Bromoacetamide) is an emerging unregulated disinfection by-product showing developmental toxicity in animals. It inactivates alcohol dehydrogenase.

Pyrvinium pamoate (Pyrvinium embonate) is an old anthelminthic medicine for the treatment of enterobiasis , which re-attracts attention as an anti-cancer drug due to its inhibition of Wnt/β-catenin pathway in some types of cancer.

4-Chloro-2'-bromoacetophenone against glycogen synthase kinase-3 (GSK-3beta).

8-Bromoadenosine is an adenosine derivative in which the hydrogen atom on the amino group is replaced by a bromine atom for the synthesis of nucleotides with specific biological activities. 8-Br-Adenosine exhibits a variety of biological activities in vitro, including inhibition of mitochondrial membrane potential, cytoplasmic Ca²⁺ levels, and RNA and protein synthesis.

Pasireotide pamoate is a stable cyclohexapeptide somatostatin mimic. Pasireotide pamoate exhibits antisecretory, antiproliferative, and proapoptotic activity.

Bromoacetamido-C2-PEG2-NH-Boc is a polyethylene glycol (PEG)-based linker with a bromoacetamido functional group and a tert-butoxycarbonyl (Boc) protecting group, used in the synthesis of proteolysis-targeting chimeras (PROTACs), which are innovative compounds for targeted protein degradation[1].

Bromoacetamido-PEG2-C2-acid is a polyethylene glycol (PEG)-based linker utilized in PROTAC synthesis[1].

Bromoacetamido-PEG2-C2-NHS ester is a PEGylation-based linker compound employed in PROTAC synthesis [1].

Bromoacetamido-PEG3-azide is a polyethylene glycol (PEG)-based linker used for the synthesis of proteolysis-targeting chimeras (PROTACs)[1].

Bromoacetamido-PEG3-C2-acid is a polyethylene glycol (PEG) derived linker utilized in the synthesis of proteolysis targeting chimeras (PROTACs)[1].

Bromoacetamido-PEG3-C2-Boc is a polyethylene glycol (PEG) derived linker suitable for the synthesis of proteolysis-targeting chimeras (PROTACs) [1].

Bromoacetamido-PEG3-NH-Boc is a polyethylene glycol (PEG)-based linker compound used in the synthesis of proteolysis-targeting chimeras (PROTACs)[1].

Bromoacetamido-PEG4-acid is a PEG-based PROTAC linker used for PROTAC synthesis[1] and serves as a cleavable 4-unit PEG ADC linker in the creation of antibody-drug conjugates (ADCs)[2].

Bromoacetamido-PEG4-C2-Boc is a polyethylene glycol (PEG)- and alkyl/ether-based linker commonly used for synthesizing proteolysis targeting chimeras (PROTACs)[1].

Bromoacetamido-PEG4-NHS ester is a PEGylated N-hydroxysuccinimide ester linker designed for PROTAC synthesis, facilitating the creation of protein-targeted chimeras (PROTACs)[1].

Bromoacetamido-PEG5-azide is a polyethylene glycol (PEG)-based linking molecule, commonly known as a PROTAC linker, which is utilized for the efficient synthesis of PROTACs[1].

Bromoacetamido-PEG8-acid, a PEG-derived PROTAC linker, is suitable for synthesizing PROTACs[1].