ml 180

ML-180 (SR1848) is a potent inverse agonist of the orphan nuclear receptor liver receptor homolog 1 (LRH-1; NR5A2) with an IC50 of 3.7 μM.

Tetracycline is an orally active broad-spectrum antibiotic that exhibits inhibitory activity against various Gram-positive and Gram-negative bacteria, as well as Chlamydia, Mycoplasma, and Rickettsia. It is commonly used in anti-infection research and can also be used to induce tumor regression based on BCR-ABL gene silencing.

Telmisartan acyl-β-D-glucuronide is a major metabolite of the angiotensin II receptor antagonist telmisartan . It does not bind human serum albumin and is cleared from rat plasma with a clearance rate of 180 ml min kg following intravenous administration.

Herquline A is an alkaloid fungal metabolite originally isolated from P. herquei. It inhibits cell death induced by influenza A strain A/PR/8/34 in MDCK cells with an IC50 value of 10 μg/ml and inhibits viral replication in a plaque assay in a concentration-dependent manner. Herquline A also inhibits platelet aggregation induced by ADP and platelet-activating factor (PAF) in vitro (IC50s = 180 and 240 μM, respectively).

Ossamycin is a macrolide antibiotic with notable antifungal properties and a relatively weak effect against Gram-positive bacteria. In cell culture studies, it inhibits L cells, Epstein-Barr ascites carcinoma cells, KB cells, Sarcoma-180 cells, L-1210 cells, and HeLa cells, with IC50 values of 0.007, 0.008, 0.005, 0.008, 0.003, and 0.005 μg/mL, respectively.

Diperamycin demonstrates activity against Gram-positive bacteria, including Enterococci and MRSA, with MIC ranging from 0.10 to 0.20 μg/mL. It also strongly inhibits the activity of cell lines L1210, P388, LS-180, KB, HeLaS3, Meth A, and B16-BL6, with IC50 values between 0.009 and 0.098 μg/mL.

5-Heneicosylresorcinol shows inhibitory effects on the release of β-hexosaminidase from RBL-2H3 cells, it also prevents triglyceride accumulation in 3T3-L1 cells. 5-Heneicosylresorcinol has nematicidal activity against nematodes Panagrellus redivivus, Cae

Lucialdehyde C (Lucidal) exhibits potent cytotoxicity against LLC, T-47D, Sarcoma 180, and Meth-A tumor cells with ED(50) values of 10.7, 4.7, 7.1, and 3.8 microg/ml, respectively.