mcvcpabsn38

Mc-VC-PAB-SN38 consists of a cleavable ADC linker (Mc-VC-PAB) and SN38, which is part of an antibody-coupled reactive molecule commonly used to synthesize antibody-coupled reactive molecules (ADCs) that target sites of action.

Anti-CCL2 (Carlumab)-MC-Vc-PAB-SN38 is an antibody-drug conjugate (ADC) composed of the human anti-CCL2 (chemokine ligand 2) antibody Carlumab, connected via the Mc-VC-PAB linker to the topoisomerase I inhibitor SN38. The toxic component and linker of the ADC is Mc-VC-PAB-SN38. This ADC is employed in cancer research studies.

Anti-SLC34A2 (Lifastuzumab)-MC-Vc-PAB-SN38 is an antibody-drug conjugate (ADC) composed of the human-derived anti-SLC34A2 (sodium-dependent phosphate transporter 2) antibody Lifastuzumab, linked with the Mc-VC-PAB connector and the topoisomeraseI inhibitor SN38. The ADC's cytotoxic component and linker are Mc-VC-PAB-SN38. This compound is utilized in cancer research.