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Results for "
mcla158
" in TargetMol Product Catalog- Inhibitors & Agonists1
- Inhibitory Antibodies1
Petosemtamab
MCLA 158
T768902213450-26-9
Petosemtamab (MCLA 158) is a highly potent monoclonal antibody against EGFR (Kd: 0.22 nM) and LGR5 (Kd: 0.86 nM). Petosemtamab promotes EGFR signaling disruption and receptor breakdown in LGR5+ cancer cells. Petosemtamab can be used in the study of solid tumors such as head and neck squamous cell carcinoma (HNSCC) and metastatic colorectal cancer (CRC).
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