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By Target- Antibody-Drug Conjugates (ADCs)
- ADC Cytotoxin(1)
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Results for "
maytansinoid dm4
" in TargetMol Product Catalog- Inhibitors & Agonists4
- Inhibitory Antibodies2
Maytansinoid DM4
T13766799840-96-3
Maytansinoid DM4, a thiol-containing maytansine derivative, is a highly potent cytotoxic moiety utilized in ADC applications.
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Indatuximab ravtansine
nBT062-DM4, BT-062
T9901A-2241238517-16-2
Indatuximab ravtansine (BT-062) is an antibody-drug conjugate (ADC) (Antibody-Drug Conjugates (ADCs)) that consists of a murine-human chimeric form based on B-B4, which specifically targets CD138, linked via a disulfide bond to the maytansinoid drug DM4. It exhibits antitumor activity.
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Tusamitamab ravtansine
SAR-408701, HuMAb2-3-SPDB-DM4
T779072254086-60-5
Tusamitamab ravtansine (SAR-408701) is a DM4-linked anti-CEACAM5 antibody-drug conjugate (ADC) comprising a humanized monoclonal antibody targeting carcinoembryonic antigen-related cell adhesion molecule-5 (CEACAM5) conjugated to a cytotoxic maytansinoid, selectively engaging CEACAM5-positive tumor cells [1].
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