lisoleucine

L-Isoleucine (Ile) is an essential branched-chain aliphatic amino acid found in many proteins. It is an isomer of LEUCINE. It is important in hemoglobin synthesis and regulation of blood sugar and energy levels.

(2S,3R,4S)-4-Hydroxyisoleucine (Hydroxyisoleucine) from fenugreek (Trigonella foenum-graecum) seeds is a potential insulinotropic (anti-diabetic) and anti-obesity amino acid that stimulates glucose-dependent insulin secretion from pancreatic cells, activates insulin receptor substrate-associated phosphoinositide 3 (PI3) kinase activity, and reduces plasma levels of triglycerides, free fatty acids, and cholesterol.

DL-Isoleucine exhibits anti-glycation activity in RAW 264.7 cells and exhibits millimolar-level cytotoxicity against SW620, CACO2, SW480, and fibroblast cells.

4-Hydroxyisoleucine (4-Hydroxy-L-isoleucine) has antidepressant-like, antidyslipidemic, and antihyperglycemic effects. It displays an insulinotropic activity.

4-Hydroxyisoleucine (Standard) is a reference standard for research and analysis in studies involving 4-Hydroxyisoleucine. 4-Hydroxyisoleucine (4-​Hydroxy-​L-​isoleucine) has antidepressant-like, antidyslipidemic, and antihyperglycemic effects. It displays an insulinotropic activity.

L-Isoleucine (Standard) is a reference standard for L-Isoleucine, suitable for quantitative analysis, quality control, and biochemical research. L-Isoleucine (Ile) is a nonpolar hydrophobic amino acid and an essential amino acid.