linase

Olverembatinib dimesylate (GZD824 Dimesylate) is a novel orally bioavailable Bcr-Abl inhibitor for Bcr-Abl(WT) and Bcr-Abl(T315I).

Olverembatinib (GZD 824) is an orally bioavailable Bcr-Abl inhibitor for Bcr-Abl(WT, IC50: 0.34 nM) and Bcr-Abl(T315I, IC50: 0.68 nM).

Penicillinase, a beta-lactamase enzyme, inactivates beta-lactam antibiotics by hydrolyzing the peptide bond of the characteristic four-membered beta-lactam ring, rendering the antibiotic ineffective [1].

Sphingomyelinase, Staphylococcus aureus (EC 3.1.4.12), is a hydrolase enzyme involved in sphingolipid metabolism. It is part of the DNase I superfamily of enzymes and is responsible for breaking down sphingomyelin (SM) into phosphocholine and ceramide.

Sphingomyelinase, Streptomyces sp. (EC 3.1.4.12), is a hydrolase enzyme involved in sphingolipid metabolism. It belongs to the DNase I superfamily and catalyzes the breakdown of sphingomyelin (SM) into phosphocholine and ceramide.

GW4869 (GW69A) is a selective and non-competitive inhibitor of neutral sphingomyelinase N-SMase (IC50=1 μM). GW4869 also inhibits exosome synthesis/release and is commonly used in exosome-related studies.Usually prepared as a suspension for experiments.

Racecadotril (Acetorphan) has been investigated for the basic science and treatment of Diarrhea, Acute Diarrhea, and Acute Gastroenteritis.

LCL521 inhibits lysosomal acid sphingomyelinase (ASMase).LCL521 is an acid ceramidase (ACDase) inhibitor.

DPTIP is an effective inhibitor of neutral sphingomyelinase 2 with an IC50 value of 30 nM.