lignan

Phyllanthin is widely used as hepatoprotective and antigenotoxic and inhibit function of P-gp.

1,6-Dihydro-4,7'-epoxy-1-methoxy-3',4'-methylenedioxy-6-oxo-3,8'-lignan is a natural product for research related to life sciences. The catalog number is TN2508 and the CAS number is 67920-48-3.

Macelignan (Anwuligan) is a lignan isolated from nutmeg with antimicrobial and anticariogenic activity against Streptococcus mutans and other streptococcus species.

Kadsuralignan A (compound 1), a dibenzocyclooctadiene lignan extracted from the leaves and stems of Schisandra lancifolia, exhibits anti-HIV activity, with an effective concentration (EC50) of 2.23 μg mL [1].

Kadsulignan H (compound 13), a lignan, exhibits inhibitory activity on nitric oxide (NO) production, presenting an IC50 value of 14.1 μM in BV-2 cells [1].

Kadsulignan C, a spirobenzofuranoid dibenzocyclooctadiene lignan, is isolated from Kadsura oblongifolia [1].

Brassilignan is a useful organic compound for research related to life sciences. The catalog number is T124524 and the CAS number is 62624-76-4.

Curlignan is a useful organic compound for research related to life sciences and the catalog number is T125318.

Rehmaneolignan A is a useful organic compound for research related to life sciences. The catalog number is T125420 and the CAS number is 2001061-00-1.

Ceplignan is a useful organic compound for research related to life sciences and the catalog number is T125512.

Maceneolignan B is a useful organic compound for research related to life sciences and the catalog number is T125684.

Saurulignan A is a useful organic compound for research related to life sciences. The catalog number is T125753 and the CAS number is 1532522-50-1.

Dimethylwulignan A1 is a useful organic compound for research related to life sciences and the catalog number is T126289.

Liconeolignan is extracted from the root of Glycyrrhiza uralensis.

Myrislignan has anti-inflammatory, and anti-cancer activities, it inhibited NF-κB signalling pathway activation, inhibited the proliferation of A549 cells in a dose- and time-dependent manner, it also significantly induced apoptosis and cell cycle arrest

Erythro-Austrobailignan-6, an orally active anti-cancer agent, inhibits DNA topoisomerase I and II activity, induces cell apoptosis, and enhances the phosphorylation of p38 and JNK.

Maceneolignan H (Compound 8), a neolignane derived from the arils of Myristica fragrans, acts as a selective CCR3 antagonist with an EC 50 value of 1.4 μM. This compound shows promise for allergic disease research [1].

Maceneolignan A, a natural product isolated from the aril of Myristica fragrans (Myristicaceae), inhibits β-hexosaminidase release in RBL-2H3 cells, exhibiting an IC50 of 48.4 μM. Additionally, it suppresses TNF-α release in antigen-stimulated RBL-2H3 cells with an IC50 of 63.7 μM [1].

1-(3,4-Dimethoxyphenyl)-2-(4-allly-2,6-dimethoxyphenoxy)propan-1-ol shows anti-staphylococcal activity against a total of five multidrug-resistant (MDR) and methicillin-resistant Staphylococcus aureus strains and the minimum inhibitory concentrations (MIC

Kadsulignan L shows in vitro antiviral effects on hepatitis B virus. It also shows moderate platelet-activating factor (PAF) antagonistic activities with the IC50 value of 2.6 x 10(-5) M.

Magnolignan A-2-O-beta-D-glucopyranoside has medium cytotoxic activity against HEp-2 and HepG2 cells, with IC(50) of 13.3 microM, and 46.4 microM, respectively.

Magnolignan C is a natural product from Magnolia officinalis.

Wulignan A1 exhibits activity against leukemia P-388 in vitro; it also may have anti-influenza virus H1N1 and H1N1-TR (a Tamiflu drug resistant virus strain) activities.

4,4'-Dihydroxy-3,3',9-trimethoxy-9,9'-epoxylignan exhibits cytotoxic activities against four tumor cell lines (A549, SK-OV-3, SKMEL-2, and HCT15).