lignan

Macelignan (Anwuligan) is a lignan isolated from nutmeg with antimicrobial and anticariogenic activity against Streptococcus mutans and other streptococcus species.

Schisandrin (Wuweizi alcohol-A) is a compound with anti-asthmatic, anti-cancer, and anti-inflammatory effects.

Schisandrin C (Wuweizisu-C) is a phytochemical lignan isolated from Schizandra chinensis Baill; shows anticancer-effects in human leukemia U937 cells.

1. Sauchinone is a useful adjunctive treatment for bacterial infection. 2. Sauchinone, an active lignan found in Saururus chinensis, to regulate the activation of HSCs, to prevent liver fibrosis, and to inhibit oxidative stress in vivo and in vitro. 3. Sa

1. Schisandrol B (Besigomsin) may exert neuroprotective effects by attenuating the microglia-mediated neuroinflammatory response via inhibiting the TLR4-mediated NF-κB and MAPKs signaling pathways. 2. Schisandrol B has anti-inflammatory property, potentially result from the inhibition of COX-2, iNOS, IL-6, TNF-α and NO through the down-regulation of RIP2 and NF-κB activation. 3. Schisandrol B induces marked protective effects against hepatic and renal injury induced by CCl(4) exposure through differential regulation of the MAPK signal transduction pathway. 4. Schisandrol B significantly inhibits cell proliferation in a dose-dependent manner, due to cell cycle arrest in the G1 phase with the downregulation of cyclin D1 expression and Retinoblastoma (RB) phosphorylation.

Diphyllin could be characterized as a new V-ATPase inhibitor in treating gastric cancer and inhibiting the phosphorylation of LRP6 in Wnt/β-catenin signaling.

Epimagnolin A is a lignan obtained from the flower buds of Magnolia fargesii, which is traditionally used in Asian medicine for treating headache and nasal congestion.

Phyllanthin is widely used as hepatoprotective and antigenotoxic and inhibit function of P-gp.

Picropodophyllone is one of the lignans from the roots of D. aurantiocaulis and D. pleianthum.

1,6-Dihydro-4,7'-epoxy-1-methoxy-3',4'-methylenedioxy-6-oxo-3,8'-lignan is a natural product for research related to life sciences. The catalog number is TN2508 and the CAS number is 67920-48-3.

Kadsuralignan A (compound 1), a dibenzocyclooctadiene lignan extracted from the leaves and stems of Schisandra lancifolia, exhibits anti-HIV activity, with an effective concentration (EC50) of 2.23 μg/mL [1].

Kadsulignan H (compound 13), a lignan, exhibits inhibitory activity on nitric oxide (NO) production, presenting an IC50 value of 14.1 μM in BV-2 cells [1].

Kadsulignan C, a spirobenzofuranoid dibenzocyclooctadiene lignan, is isolated from Kadsura oblongifolia [1].

Brassilignan is a useful organic compound for research related to life sciences. The catalog number is T124524 and the CAS number is 62624-76-4.

Curlignan is a useful organic compound for research related to life sciences and the catalog number is T125318.

Rehmaneolignan A is a useful organic compound for research related to life sciences. The catalog number is T125420 and the CAS number is 2001061-00-1.

Ceplignan is a useful organic compound for research related to life sciences and the catalog number is T125512.

Maceneolignan B is a useful organic compound for research related to life sciences and the catalog number is T125684.

Saurulignan A is a useful organic compound for research related to life sciences. The catalog number is T125753 and the CAS number is 1532522-50-1.

Dimethylwulignan A1 is a useful organic compound for research related to life sciences and the catalog number is T126289.

Liconeolignan is extracted from the root of Glycyrrhiza uralensis.

Myrislignan has anti-inflammatory, and anti-cancer activities, it inhibited NF-κB signalling pathway activation, inhibited the proliferation of A549 cells in a dose- and time-dependent manner, it also significantly induced apoptosis and cell cycle arrest

Erythro-Austrobailignan-6, an orally active anti-cancer agent, inhibits DNA topoisomerase I and II activity, induces cell apoptosis, and enhances the phosphorylation of p38 and JNK.

Maceneolignan H (Compound 8), a neolignane derived from the arils of Myristica fragrans, acts as a selective CCR3 antagonist with an EC 50 value of 1.4 μM. This compound shows promise for allergic disease research [1].