l-citrulline

L-Citrulline, an amino acid, is derived from ornithine during the catabolism of proline, glutamate, or glutamine, and also from L-arginine via the arginine-citrulline pathway.

L-Citrulline-d6 is the deuterated form of L-Citrulline. L-Citrulline is an amino acid derived from ornithine, which results from the catabolism of proline, glutamine, and glutamate, or obtained through the arginine-citrulline pathway involving l-arginine.

L-Citrulline-d4 is the deuterated form of L-Citrulline. L-Citrulline, an amino acid, is derived from the catabolic processes involving ornithine, originating from the breakdown of proline, glutamine, and glutamates, or it can be obtained through the l-arginine pathway known as the arginine-citrulline cycle.

L-Citrulline-13C is L-Citrulline labeled with 13C. This amino acid is derived from the breakdown of ornithine, which originates from the catabolism of proline, glutamine, and glutamate salts, or it can be obtained from l-arginine through the arginine-citrulline pathway.

L-Citrulline-d7 is the deuterated form of L-Citrulline. L-Citrulline is an amino acid derived from the catabolism of ornithine, which stems from proline, glutamine, and glutamate, or it can be obtained through the arginine-citrulline pathway from l-arginine.

L-Citrulline (Standard) is available for quantitative analysis.) L-Citrulline is a non-essential amino acid involved in the nitric oxide cycle and the urea cycle, promotes vasodilatation, has antioxidant and anti-inflammatory properties, is orally available, and crosses the blood-brain barrier through LAT1. It is an agonist of eNOS (endothelial nitric oxide synthase), iNOS (inducible nitric oxide synthase), and mTORC1 (rapamycin targeting protein complex 1), and an inhibitor of SREBP-1 (sterol regulatory element binding protein 1).

L-Citrulline-13C (Standard) is a reference standard of L-Citrulline-13C intended for quantitative analysis, quality control, and related biochemical research applications. L-Citrulline-13C is L-Citrulline labeled with 13C. This amino acid is derived from the breakdown of ornithine, which originates from the catabolism of proline, glutamine, and glutamate salts, or it can be obtained from l-arginine through the arginine-citrulline pathway.

L-Citrulline-D7 (Standard) is a reference standard of L-Citrulline-D7 intended for quantitative analysis, quality control, and related biochemical research applications. L-Citrulline-d7 is the deuterated form of L-Citrulline. L-Citrulline is an amino acid derived from the catabolism of ornithine, which stems from proline, glutamine, and glutamate, or it can be obtained through the arginine-citrulline pathway from l-arginine.

L-Citrulline-CoA (L-Citrulline-coenzyme A) is a derivative of Coenzyme A.

N-Acetyl-L-citrulline-CoA (N-Acetyl-L-ctrulline-coenzyme A) is a derivative of coenzyme A.

2-Amino-5-ureidopentanoic acid (Citrulline) exists in the liver, is not a protein component, is an important intermediate in the human urea cycle, can be combined with ornithine, arginine to treat hyperammonemia.

Citrulline malate is a cpd of anti-fatigue.

MC-Val-Cit-PABC-PNP, also known as Mc-Val-Cit-PABC-PNP, is a cathepsin cleavable ADC peptide linker. For example, FDA approved drug, brentuximab vedotin, adopts this linker. Protein- and peptide-drug conjugates hold a promising stance in the delivery of therapeutic agents by providing distinct advantage of improving therapeutic potential of drugs. Use of specialized linkers makes them unique in their in vivo therapeutic application by providing target tissue-specific release of drug.

L-Homocitrulline (Homocitrulline) is a metabolite that can be detected in larger amounts in the urine of individuals with urea cycle disorders. The accumulation of carbamyl phosphate due to a depleted supply of ornithine for the urea cycle may be responsible for the enhanced synthesis of L-Homocitrulline and homoarginine in some cases.

L-Arginine (L-Arg) is a substrate of endothelial nitric oxide synthase (eNOS). L-Arginine is transported to vascular smooth muscle cells via a family of cationic amino acid transporters and is metabolized to nitric oxide, polyamines, or L-proline. L-Arginine is a potent vasodilator and can be used to induce experimental acute pancreatitis.

D-Citrulline (H-D-Cit-OH), a stereoisomer of L-citrulline, effectively reduces cardiac contractile dysfunction caused by polymorphonuclear leukocyte (PMN) in isolated perfused rat hearts undergoing ischemia/reperfusion. This protective effect is mediated through a non-NO-mediated mechanism.

NG-Hydroxy-L-arginine acetate (NOHA acetate) acts as a crucial physiological inhibitor of arginase, playing a vital role in the conversion of arginine to nitric oxide and citrulline via nitric oxide synthase.