l-citrulline

L-Citrulline, an amino acid, is derived from ornithine during the catabolism of proline, glutamate, or glutamine, and also from L-arginine via the arginine-citrulline pathway.

2-Amino-5-ureidopentanoic acid (Citrulline) exists in the liver, is not a protein component, is an important intermediate in the human urea cycle, can be combined with ornithine, arginine to treat hyperammonemia.

L-Homocitrulline (Homocitrulline) is a metabolite that can be detected in larger amounts in the urine of individuals with urea cycle disorders. The accumulation of carbamyl phosphate due to a depleted supply of ornithine for the urea cycle may be responsible for the enhanced synthesis of L-Homocitrulline and homoarginine in some cases.

L-Arginine (L-Arg) is a substrate of endothelial nitric oxide synthase (eNOS). L-Arginine is transported to vascular smooth muscle cells via a family of cationic amino acid transporters and is metabolized to nitric oxide, polyamines, or L-proline. L-Arginine is a potent vasodilator and can be used to induce experimental acute pancreatitis.

Citrulline malate is a cpd of anti-fatigue.