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l-524-0366

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L524-0366
[1-(3-chlorophenyl)triazol-4-yl]-thiomorpholino-methanone
T8570951612-19-4
L524-0366 is a selective Fn14 receptor antagonist that exerts its effects through competitive binding to the Fn14 receptor. L524-0366 specifically binds to the Fn14 receptor surface, with a KD of 7.12 μM. At a concentration of 10 μM, L524-0366 completely inhibits TWEAK-induced glial cell migration and exhibits no cytotoxicity at concentrations below 50 μM. L524-0366 possesses antitumor and anti-inflammatory activity and is widely used in research on diseases such as cancer.
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