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kras g12c inhibitor 15

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  • Inhibitors & Agonists
    4
    TargetMol | Inhibitors_Agonists
KRAS G12C inhibitor 15
T117692349393-21-9
KRAS G12C inhibitor 15 is a potent inhibitor of the KRAS G12C protein.
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10-14 weeks
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KRASG12C IN-14
T200204
KRASG12C IN-14 (compound 15), a potent inhibitor specifically designed for the KRAS G12C mutation, exhibits impressive efficacy in impeding CYPA-dependent KRAS-BRAF interaction and ERK phosphorylation in NCI-H358 cells, both with an IC 50 of 0.002 μM.
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RAS/RAS-RAF-IN-1
T366422447039-81-6
RAS RAS-RAF-IN-1 is a potent inhibitor of RAS and RAS-RAF, exhibiting a KD of 5.0 μμ-15 μμ for cyclophilin A (CYPA) binding affinity and demonstrating antitumor activity[1].
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kras inhibitor-15
T627372230873-75-1
KRAS inhibitor-15 (compound 3-19) is a potent inhibitor of KRAS G12C with an IC50 of 0.954 μM. It exhibits p-ERK inhibition in MIA PaCA-2 and A549 cells with IC50s of 2.03 μM and >33.3 μM, respectively. KRAS inhibitor-15 has potential for study in pancreatic, colorectal, and lung cancers.
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6-8 weeks
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